A Fast Calibration Method for Pneumotachograph with a 3L Syringe

Author:

Li Yueqi12,Qiu Xin12,Zhang Hao23,Xu Lirui23ORCID,Lu Saihu23,Du Lidong234ORCID,Chen Xianxiang234,Fang Zhen234

Affiliation:

1. Institute of Microelectronic, Chinese Academy of Sciences (IMECAS), Beijing 100029, China

2. Aerospace Information Research Institute, Chinese Academy of Sciences (AIRCAS), Beijing 100190, China

3. Personalized Management of Chronic Respiratory Disease, Chinese Academy of Medical Sciences, Beijing 100006, China

4. University of Chinese Academy of Sciences, Beijing 100190, China

Abstract

The pneumotachograph (PNT), a commonly used flowmeter in pulmonary function diagnostic equipment, is the required frequency calibration to maintain high accuracy. Aiming to simplify calibration steps, we developed a fast calibration system with a commercially available 3L syringe to provide a real output flow waveform. The acquisition of the real output flow waveform is based on the reliable measurement of in-cylinder pressure and the real-time detection of plunger speed. To improve the calibration accuracy, the tapping position for measuring in-cylinder pressure was optimized by CFD dynamic-mesh updating technique. The plunger speed was obtained by tracking the handle of the plunger with a smart terminal. Then, the real output flow was corrected using a compensation model equation. The calibration system was verified by the pulmonary waveform generator that the accuracy satisfied the requirements for respiratory flow measurement according to ATS standardization. The experimental results suggest that the developed method promises the fast calibration of PNT.

Funder

National Key Research and Development Project

National Natural Science Foundation of China

CAMS Innovation Fund for Medical Sciences

Publisher

MDPI AG

Subject

Bioengineering

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