A Disentangled VAE-BiLSTM Model for Heart Rate Anomaly Detection

Author:

Staffini Alessio123ORCID,Svensson Thomas145ORCID,Chung Ung-il146ORCID,Svensson Akiko Kishi157ORCID

Affiliation:

1. Precision Health, Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan

2. Advanced Technology Department, ALBERT Inc., Shinjuku Front Tower 15F, 2-21-1, Kita-Shinjuku, Shinjuku-ku, Tokyo 169-0074, Japan

3. Department of Economics and Finance, Catholic University of Milan, Largo Gemelli 1, 20123 Milan, Italy

4. Graduate School of Health Innovation, Kanagawa University of Human Services, Research Gate Building Tonomachi 2-A 2, 3F, 3-25-10 Tonomachi, Kawasaki-ku, Kawasaki-shi 210-0821, Japan

5. Department of Clinical Sciences, Skåne University Hospital, Lund University, 205 02 Malmö, Sweden

6. Clinical Biotechnology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan

7. Department of Diabetes and Metabolic Diseases, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

Abstract

Cardiovascular diseases (CVDs) remain a leading cause of death globally. According to the American Heart Association, approximately 19.1 million deaths were attributed to CVDs in 2020, in particular, ischemic heart disease and stroke. Several known risk factors for CVDs include smoking, alcohol consumption, lack of regular physical activity, and diabetes. The last decade has been characterized by widespread diffusion in the use of wristband-style wearable devices which can monitor and collect heart rate data, among other information. Wearable devices allow the analysis and interpretation of physiological and activity data obtained from the wearer and can therefore be used to monitor and prevent potential CVDs. However, these data are often provided in a manner that does not allow the general user to immediately comprehend possible health risks, and often require further analytics to draw meaningful conclusions. In this paper, we propose a disentangled variational autoencoder (β-VAE) with a bidirectional long short-term memory network (BiLSTM) backend to detect in an unsupervised manner anomalies in heart rate data collected during sleep time with a wearable device from eight heterogeneous participants. Testing was performed on the mean heart rate sampled both at 30 s and 1 min intervals. We compared the performance of our model with other well-known anomaly detection algorithms, and we found that our model outperformed them in almost all considered scenarios and for all considered participants. We also suggest that wearable devices may benefit from the integration of anomaly detection algorithms, in an effort to provide users more processed and straightforward information.

Funder

the Center of Innovation Program from the Japan Science and Technology Agency

Kanagawa Prefecture

Publisher

MDPI AG

Subject

Bioengineering

Reference86 articles.

1. World Health Organization (2023, January 20). Cardiovascular Diseases. Available online: https://www.who.int/health-topics/cardiovascular-diseases#tab=tab_1.

2. American Heart Association (2023, January 20). 2022 Heart Disease & Stroke Statistical Update Fact Sheet Global Burden of Disease. Available online: https://professional.heart.org/-/media/PHD-Files-2/Science-News/2/2022-Heart-and-Stroke-Stat-Update/2022-Stat-Update-factsheet-GIobal-Burden-of-Disease.pdf.

3. Centers for Disease Control and Prevention, and National Center for Health Statistics (2022, February 21). About Multiple Cause of Death, 1999–2020, Available online: https://wonder.cdc.gov/mcd-icd10.html.

4. Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association;Tsao;Circulation,2022

5. The Global Burden of Cardiovascular Diseases and Risk Factors: 2020 and Beyond;Mensah;J. Am. Coll. Cardiol.,2019

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