Abstract
Exosomes act as emerging transdermal drug delivery vehicles with high deformability and excellent permeability, which can be used to deliver various small-molecule drugs and macromolecular drugs and increase the transdermal and dermal retention of drugs, improving the local efficacy and drug delivery compliance. At present, there are many studies on the use of plant exosome-like nanoparticles (PELNVs) as drug carriers. In this review, the source, extraction, isolation, and chemical composition of plant exosomes are reviewed, and the research progress on PELNVs as drug delivery systems in transdermal drug delivery systems in recent years has elucidated the broad application prospect of PELNVs.
Funder
Natural Science Foundation of Guangdong Province
Guangzhou Research and Development Plan in Key Fields
R&D Plan Project in Key Fields of Guangdong Province
Reference92 articles.
1. Research progress of transdermal drug delivery system of traditional Chinese medicine and the application of new formulations;Jing;Chin. J. New Drugs,2019
2. Research Progress of Transdermal Drug Delivery System;Jiaqi;Prog. Biomed. Eng.,2022
3. Recent advance of nanocarriers in transdermal drug delivery of traditional Chinese medicine;Guiying;West China J. Pharm. Sci.,2020
4. Najahi-Missaoui, W., Arnold, R.D., and Cummings, B.S. (2020). Safe nanoparticles: Are we there yet?. Int. J. Mol. Sci., 22.
5. Plant derived edible nanoparticles as a new therapeutic approach against diseases;Zhang;Tissue Barriers,2016
Cited by
19 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献