Quantitative and Compositional MRI of the Articular Cartilage: A Narrative Review

Author:

Albano Domenico12ORCID,Viglino Umberto3ORCID,Esposito Francesco4,Rizzo Aldo5ORCID,Messina Carmelo16,Gitto Salvatore16ORCID,Fusco Stefano16,Serpi Francesca16,Kamp Benedikt7ORCID,Müller-Lutz Anja7ORCID,D’Ambrosi Riccardo16ORCID,Sconfienza Luca Maria16ORCID,Sewerin Philipp89ORCID

Affiliation:

1. IRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy

2. Dipartimento di Scienze Biomediche, Chirurgiche ed Odontoiatriche, Università degli Studi di Milano, 20122 Milan, Italy

3. Unit of Radiology, Ospedale Evangelico Internazionale, 16100 Genova, Italy

4. Division of Radiology, Department of Precision Medicine, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy

5. Postgraduate School of Diagnostic and Interventional Radiology, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milan, Italy

6. Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, 20122 Milan, Italy

7. Department of Diagnostic and Interventional Radiology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany

8. Rheumazentrum Ruhrgebiet, Ruhr University Bochum, 44649 Herne, Germany

9. Department and Hiller-Research-Unit for Rheumatology, Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany

Abstract

This review examines the latest advancements in compositional and quantitative cartilage MRI techniques, addressing both their potential and challenges. The integration of these advancements promises to improve disease detection, treatment monitoring, and overall patient care. We want to highlight the pivotal task of translating these techniques into widespread clinical use, the transition of cartilage MRI from technical validation to clinical application, emphasizing its critical role in identifying early signs of degenerative and inflammatory joint diseases. Recognizing these changes early may enable informed treatment decisions, thereby facilitating personalized medicine approaches. The evolving landscape of cartilage MRI underscores its increasing importance in clinical practice, offering valuable insights for patient management and therapeutic interventions. This review aims to discuss the old evidence and new insights about the evaluation of articular cartilage through MRI, with an update on the most recent literature published on novel quantitative sequences.

Publisher

MDPI AG

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