Expression of C Reactive Protein in Gingival Crevicular Fluid of Patients with Periodontitis Wearing Metal-Ceramic Dental Crowns

Author:

Dimofte Alina-Ramona1,Gheorghe Dorin Nicolae2ORCID,Popescu Dora Maria2,Mitruț Ioana3ORCID,Mărășescu Petre Costin3,Manolea Horia Octavian4,Boldeanu Mihail Virgil5ORCID,Şurlin Petra2

Affiliation:

1. Doctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania

2. Research Center of Periodontal-Systemic Implications, Department of Periodontology, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania

3. Department of Dental Prosthesis Technology, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania

4. Department of Dental Materials, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania

5. Department of Immunology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania

Abstract

Metal-ceramic crowns (MC) have long been considered as gold standard for dental prosthetic restorations. Our study aims to evaluate the influence of MC, with conventional technology used for the framework, on the periodontal parameters and levels of C reactive protein, an inflammatory marker, in gingival crevicular fluid in patients diagnosed with periodontitis. Two groups were established: the test group T-28 teeth from the lateral area wearing a MC crown and the control group C-28 teeth without any wearing. These parameters were evaluated: probing depth, Gingival Index, and longevity of crowns. The quantitative assessment through enzyme-linked immunosorbent assay of the targeted pro-inflammatory mediator was performed. There is a difference statistically significant between the groups T and C regarding the marker’s levels and gingival index, a very strong correlation between these levels and probing depth and a strong correlation between longevity and Gingival Index. Periodontal clinical parameters are more pronounced the longer the time elapsed since the application of the crowns. Expression of C reactive protein is higher in the presence of MC crowns.

Publisher

MDPI AG

Subject

Fluid Flow and Transfer Processes,Computer Science Applications,Process Chemistry and Technology,General Engineering,Instrumentation,General Materials Science

Reference37 articles.

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