Association between Obstructive Sleep Apnea and Chronic Kidney Disease According to Sex, Long Working Hours: The Korean National Health and Nutrition Examination Survey (2019–2020)
Author:
Jung Sung-Min1ORCID, Lee Mee-Ri2ORCID
Affiliation:
1. Department of Surgery, Inje University, Ilsan Paik Hospital, Goyang-si 10380, Republic of Korea 2. Department of Preventive Medicine, Soonchunhyang University College of Medicine, Cheonan-si 31151, Republic of Korea
Abstract
This study aimed to investigate whether obstructive sleep apnea (OSA) is associated with an increased risk of chronic kidney disease (CKD) and to perform subgroup analysis by sex and working hours. This cross-sectional study was conducted on 8157 subjects who participated in the Korea National Health and Nutrition Examination Survey (KNHANES). The adults completed the STOP-BANG score to measure their risk of OSA, and blood and urine samples were collected to ascertain the severity of CKD based on the estimated glomerular filtration rate and urine albumin-to-creatinine ratio. Multivariate logistic regression was used for complex sample analysis. After fully adjusting for the confounding variables, the high-risk OSA group showed a significantly higher risk of developing albuminuria and CKD than the low-risk group, particularly among men. Odds ratio (OR) 1.72, 95% confidence interval (CI) 1.13–2.6 and (OR 1.67, 95% CI 1.14–2.45), respectively. Additionally, men who worked for 40 h/week showed a significant association between OSA, CKD, and albuminuria. This study supports the link between OSA and the risk of kidney disease, especially among men and those who work long hours. Screening and treating OSA may be a crucial strategy for preventing kidney disease, particularly in high-risk populations.
Funder
Soonchunhyang University Research Fund
Subject
Paleontology,Space and Planetary Science,General Biochemistry, Genetics and Molecular Biology,Ecology, Evolution, Behavior and Systematics
Reference41 articles.
1. (2023, January 19). Obstructive Sleep Apnea, Available online: https://www.ncbi.nlm.nih.gov/books/NBK459252/. 2. Estimation of the global prevalence and burden of obstructive sleep apnoea: A literature-based analysis;Benjafield;Lancet Respir. Med.,2019 3. Increased prevalence of sleep-disordered breathing in adults;Peppard;Am. J. Epidemiol.,2013 4. Santilli, M., Manciocchi, E., D’Addazio, G., Di Maria, E., D’Attilio, M., Femminella, B., and Sinjari, B. (2021). Prevalence of Obstructive Sleep Apnea Syndrome: A Single-Center Retrospective Study. Int. J. Environ. Res. Public Health, 18. 5. Su, X., Li, J.H., Gao, Y., Chen, K., Gao, Y., Guo, J.J., Shi, M., Zou, X., Xu, W., and Zhao, L.B. (2021). Impact of obstructive sleep apnea complicated with type 2 diabetes on long-term cardiovascular risks and all-cause mortality in elderly patients. BMC Geriatr., 21.
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