Targeting Subviral Particles: A Critical Step in Achieving HBV Functional Cure but Where Are We with Current Agents in Clinical Development?

Author:

Vaillant Andrew

Abstract

The recent review [...]

Publisher

MDPI AG

Subject

Virology,Infectious Diseases

Reference48 articles.

1. HBsAg Loss as a Treatment Endpoint for Chronic HBV Infection: HBV Cure

2. Editorial: In vitro mechanistic evaluation of nucleic acid polymers: A cautionary tale

3. Safety, Tolerability and Pharmacokinetics (PK) of Single and Multiple Doses of ALG-010133, an S-antigen Transport Inhibiting Oligonucleotide Polymer (STOPS) for the Treatment of Chronic Hepatitis B;Gane;J. Hepatol.,2021

4. Aligos Halting Further Development of STOPS™ Drug Candidate, ALG-010133 https://investor.aligos.com/news-releases/news-release-details/aligos-halting-further-development-stopstm-drug-candidate-alg/

5. REP 2139: Antiviral Mechanisms and Applications in Achieving Functional Control of HBV and HDV Infection

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