Abstract
Hepatocellular carcinoma (HCC) remains one of the most common malignancies and the third cause of cancer-related death worldwide, with surgery being the best prognostic tool. Among the well-known causative factors of HCC are chronic liver virus infections, chronic virus hepatitis B (HBV) and chronic hepatitis virus C (HCV), aflatoxins, tobacco consumption, and non-alcoholic liver disease (NAFLD). There is a need for the development of efficient molecular markers and alternative therapeutic targets of great significance. In this review, we describe the general characteristics of HCC and present a variety of targeted therapies that resulted in progress in HCC therapy.
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis
Reference208 articles.
1. Hepatocellular carcinoma: Current trends in worldwide epidemiology, risk factors, diagnosis, and therapeutics;Hepat. Med.,2012
2. The global epidemiology of hepatocellular carcinoma: Present and future;Clin. Liver. Dis.,2011
3. Age-specific sex difference in the incidence of hepatocellular carcinoma in the United States;Oncotarget,2017
4. From diagnosis to treatment of hepatocellular carcinoma: An epidemic problem for both developed and developing world;World J. Gastroenterol.,2017
5. Intensive care unit outcomes following orthotopic liver transplantation: Single-center experience and review of the literature;G. Chir.,2019
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