BDNF as a Mediator of Antidepressant Response: Recent Advances and Lifestyle Interactions-Reference-Cited by-同舟云学术

BDNF as a Mediator of Antidepressant Response: Recent Advances and Lifestyle Interactions

Published:2022-11-21 Issue:22 Volume:23 Page:14445
ISSN:1422-0067
Container-title:International Journal of Molecular Sciences
language:en
Short-container-title:IJMS

Author:

Cubillos Susana,Engmann Olivia,Brancato Anna^ORCID

Abstract

Conventional antidepressants are widely employed in several psychiatric and neurologic disorders, yet the mechanisms underlying their delayed and partial therapeutic effects are only gradually being understood. This narrative review provides an up-to-date overview of the interplay between antidepressant treatment and Brain-Derived Neurotrophic Factor (BDNF) signaling. In addition, the impact of nutritional, environmental and physiological factors on BDNF and the antidepressant response is outlined. This review underlines the necessity to include information on lifestyle choices in testing and developing antidepressant treatments in the future.

Funder

Carl-Zeiss-Foundation

European Union—NextGenerationEU

University of Palermo

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

Link

https://www.mdpi.com/1422-0067/23/22/14445/pdf

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