Titanium-45 (45Ti) Radiochemistry and Applications in Molecular Imaging

Author:

Saini Shefali12,Lapi Suzanne E.12ORCID

Affiliation:

1. Department of Radiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA

2. Department of Chemistry, University of Alabama at Birmingham, Birmingham, AL 35294, USA

Abstract

Molecular imaging is an important part of modern medicine which enables the non-invasive identification and characterization of diseases. With the advancement of radiochemistry and scanner technology, nuclear medicine is providing insight into efficient treatment options for individual patients. Titanium-45 (45Ti) is a lesser-explored radionuclide that is garnering increasing interest for the development of positron emission tomography (PET) radiopharmaceuticals. This review discusses aspects of this radionuclide including production, purification, radiochemistry development, and molecular imaging studies.

Funder

Department of Energy University Isotope Network

Publisher

MDPI AG

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