Study on the Microwave Ablation Effect of Inflated Porcine Lung

Abstract

(1) Background: Microwave ablation (MWA) has an efficient killing effect on primary and metastatic lung cancer. However, the treatment effect will be affected by the air in the lung, which makes it very difficult to accurately predict and control the ablation area; (2) Methods: In this paper, in vitro experiments combined with simulations are used to study the microwave ablation area of inflated porcine lung. The in vitro experiment is divided into inflated group and deflated group, combined with different ablation power (40 W, 50 W, 60 W) and ablation time (100 s, 200 s, 300 s) for experiment, each power and time combination are repeated five times. A total of 90 ablation experiments were performed. The simulation experiment uses COMSOL Multiphysics software to simulate the microwave ablation area of the inflated lung; (3) Results and Conclusions: When the ablation power is 40 W, 50 W, and 60 W, the average long diameter of the deflated group are 20.8–30.9%, 7.6–22.6%, 10.4–19.8% larger than those of the inflated group, respectively; the average short diameter of the deflated group is 24.5–41.4%, 31.6–45.7%, 27.3–42.9% larger than that of the inflated group. The results show that the ablation area of inflated lung is smaller than deflated lung, which is mainly due to the smaller ablation short diameter.