Effects of Habitual Dietary Change on the Gut Microbiota and Health of Silkworms
-
Published:2024-01-31
Issue:3
Volume:25
Page:1722
-
ISSN:1422-0067
-
Container-title:International Journal of Molecular Sciences
-
language:en
-
Short-container-title:IJMS
Author:
Wang Guang12, Ding Xueyan12, Yang Jiameng12, Ma Lu12, Sun Xiaoning12, Zhu Ruihong12, Lu Riming12, Xiao Zhitian12, Xing Zhiyi12, Liu Jingbin12, Pan Zhonghua12, Xu Shiqing12ORCID, Sima Yanghu12
Affiliation:
1. School of Biology and Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou 215123, China 2. Institute of Agricultural Biotechnology & Ecology (IABE), Soochow University, Suzhou 215123, China
Abstract
Diet plays a crucial role in shaping the gut microbiota and overall health of animals. Traditionally, silkworms are fed fresh mulberry leaves, and artificial diets do not support good health. The aim of this study was to explore the relationship between the dietary transition from artificial diets to mulberry leaves and the effects on the gut microbiota and physiological changes in silkworms as a model organism. With the transition from artificial diets to mulberry leaves, the diversity of the silkworm gut microbiota increased, and the proportion of Enterococcus and Weissella, the dominant gut bacterial species in silkworms reared on artificial diets, decreased, whereas the abundance of Achromobacter and Rhodococcus increased. Dietary transition at different times, including the third or fifth instar larval stages, resulted in significant differences in the growth and development, immune resistance, and silk production capacity of silkworms. These changes might have been associated with the rapid adaptation of the intestinal microbiota of silkworms to dietary transition. This study preliminarily established a dietary transition–gut microbial model in silkworms based on the conversion from artificial diets to mulberry leaves, thus providing an important reference for future studies on the mechanisms through which habitual dietary changes affect host physiology through the gut microbiome.
Funder
China Agriculture Research System of MOF and MARA the Priority Academic Program Development of Jiangsu Higher Education Institutions
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis
Reference58 articles.
1. Leveraging diet to engineer the gut microbiome;Wolter;Nat. Rev. Gastroenterol. Hepatol.,2021 2. You are what you eat: Diet, health and the gut microbiota;Zmora;Nat. Rev. Gastroenterol. Hepatol.,2019 3. The lung-brain axis: A new frontier in host-microbe interactions;Azzoni;Immunity,2022 4. Gut microbiota in human metabolic health and disease;Fan;Nat. Rev. Microbiol.,2021 5. Yuan, S., Sun, Y., Chang, W., Zhang, J., Sang, J., Zhao, J., Song, M., Qiao, Y., Zhang, C., and Zhu, M. (2023). The silkworm (Bombyx mori) gut microbiota is involved in metabolic detoxification by glucosylation of plant toxins. Commun. Biol., 6.
|
|