High-Flow Tracheal Oxygen for Tracheostomy Tube Removal in Lung Transplant Recipients

Author:

Lionello Federico1,Guarnieri Gabriella1ORCID,Arcaro Giovanna1,Bertagna De Marchi Leonardo1,Molena Beatrice1,Contessa Cristina2ORCID,Boscolo Annalisa13ORCID,Rea Federico1,Navalesi Paolo3ORCID,Vianello Andrea14ORCID

Affiliation:

1. Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, 35131 Padova, Italy

2. Department of Directional Hospital Management, University of Padova, 35131 Padova, Italy

3. Department of Medicine, University of Padova, 35131 Padova, Italy

4. Fisiopatologia Respiratoria, Ospedale-Università di Padova, Via Giustiniani, 2, 35128 Padova, Italy

Abstract

(1) Background: Because of a complicated intraoperative course and/or poor recovery of graft function, approximately 15% of lung transplant (LT) recipients require prolonged mechanical ventilation (PMV) and receive a tracheostomy. This prospective study aimed to assess the effect of High-Flow Tracheal Oxygen (HFTO) on tracheostomy tube removal in LT recipients receiving PMV postoperatively. (2) Methods: The clinical course of 14 LT recipients receiving HFTO was prospectively evaluated and compared to that of 13 comparable controls receiving conventional oxygen therapy (COT) via tracheostomy. The study’s primary endpoint was the number of patients whose tracheostomy tube was removed at discharge from an Intermediate Respiratory Care Unit (IRCU). (3) Results: Setting up HFTO proved easy, and it was well tolerated by all the patients. The number of patients whose tracheostomy tube was removed was significantly higher in the HFOT group compared to the COT group [13/14 vs. 6/13 (p = 0.0128)]. (4) Conclusions: HFTO is an effective, safe therapy that facilitates tracheostomy tube removal in LT recipients after weaning from PMV.

Funder

Unione Trapiantati di Polmone—Padova OdV

Publisher

MDPI AG

Subject

General Medicine

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