Nanomedicine: New Frontiers in Fighting Microbial Infections

Author:

Mehrabi Mohammad Reza1ORCID,Soltani Madjid2345ORCID,Chiani Mohsen1ORCID,Raahemifar Kaamran678ORCID,Farhangi Ali1

Affiliation:

1. Department of NanoBiotechnology, Pasteur Institute of Iran, Tehran 13169-43551, Iran

2. Department of Mechanical Engineering, K. N. Toosi University of Technology, Tehran 19967-15433, Iran

3. Advanced Bioengineering Initiative Center, Multidisciplinary International Complex, K. N. Toosi University of Technology, Tehran 14176-14411, Iran

4. Centre for Biotechnology and Bioengineering (CBB), University of Waterloo, Waterloo, ON N2L 3G1, Canada

5. Department of Electrical and Computer Engineering, University of Waterloo, Waterloo, ON N2L 3G1, Canada

6. Data Science and Artificial Intelligence Program, College of Information Sciences and Technology (IST), Penn State University, State College, PA 16801, USA

7. Department of Chemical Engineering, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada

8. School of Optometry and Vision Science, Faculty of Science, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada

Abstract

Microbes have dominated life on Earth for the past two billion years, despite facing a variety of obstacles. In the 20th century, antibiotics and immunizations brought about these changes. Since then, microorganisms have acquired resistance, and various infectious diseases have been able to avoid being treated with traditionally developed vaccines. Antibiotic resistance and pathogenicity have surpassed antibiotic discovery in terms of importance over the course of the past few decades. These shifts have resulted in tremendous economic and health repercussions across the board for all socioeconomic levels; thus, we require ground-breaking innovations to effectively manage microbial infections and to provide long-term solutions. The pharmaceutical and biotechnology sectors have been radically altered as a result of nanomedicine, and this trend is now spreading to the antibacterial research community. Here, we examine the role that nanomedicine plays in the prevention of microbial infections, including topics such as diagnosis, antimicrobial therapy, pharmaceutical administration, and immunizations, as well as the opportunities and challenges that lie ahead.

Publisher

MDPI AG

Subject

General Materials Science,General Chemical Engineering

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