Nanomedicine: New Frontiers in Fighting Microbial Infections

Author:

Mehrabi Mohammad Reza1ORCID,Soltani Madjid2345ORCID,Chiani Mohsen1ORCID,Raahemifar Kaamran678ORCID,Farhangi Ali1

Affiliation:

1. Department of NanoBiotechnology, Pasteur Institute of Iran, Tehran 13169-43551, Iran

2. Department of Mechanical Engineering, K. N. Toosi University of Technology, Tehran 19967-15433, Iran

3. Advanced Bioengineering Initiative Center, Multidisciplinary International Complex, K. N. Toosi University of Technology, Tehran 14176-14411, Iran

4. Centre for Biotechnology and Bioengineering (CBB), University of Waterloo, Waterloo, ON N2L 3G1, Canada

5. Department of Electrical and Computer Engineering, University of Waterloo, Waterloo, ON N2L 3G1, Canada

6. Data Science and Artificial Intelligence Program, College of Information Sciences and Technology (IST), Penn State University, State College, PA 16801, USA

7. Department of Chemical Engineering, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada

8. School of Optometry and Vision Science, Faculty of Science, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada

Abstract

Microbes have dominated life on Earth for the past two billion years, despite facing a variety of obstacles. In the 20th century, antibiotics and immunizations brought about these changes. Since then, microorganisms have acquired resistance, and various infectious diseases have been able to avoid being treated with traditionally developed vaccines. Antibiotic resistance and pathogenicity have surpassed antibiotic discovery in terms of importance over the course of the past few decades. These shifts have resulted in tremendous economic and health repercussions across the board for all socioeconomic levels; thus, we require ground-breaking innovations to effectively manage microbial infections and to provide long-term solutions. The pharmaceutical and biotechnology sectors have been radically altered as a result of nanomedicine, and this trend is now spreading to the antibacterial research community. Here, we examine the role that nanomedicine plays in the prevention of microbial infections, including topics such as diagnosis, antimicrobial therapy, pharmaceutical administration, and immunizations, as well as the opportunities and challenges that lie ahead.

Publisher

MDPI AG

Subject

General Materials Science,General Chemical Engineering

Reference222 articles.

1. Trends in Infectious Disease Mortality in the United States During the 20th Century;Armstrong;JAMA,1999

2. Changing patterns of infectious disease;Cohen;Nature,2000

3. Drug-delivery Ca-Mg silicate scaffolds encapsulated in PLGA;Jadidi;Int. J. Pharm.,2020

4. World Health Organization (WHO) (2020, October 28). Global Health Estimates 2016: Disease Burden by Cause, Age, Sex, by Country and by region, 2000–2016. Available online: https://www.who.int/healthinfo/global_burden_disease/estimates/en/index1.html.

5. Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhea: The Global Burden of Disease Study 1990–2016;Khalil;Lancet Infect. Dis.,2018

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3