Enhanced Ionic Polymer–Metal Composites with Nanocomposite Electrodes for Restoring Eyelid Movement of Patients with Ptosis

Author:

Hosseini Sara Sadat1,Yamini Bakhtiar1,Ichkitidze Levan23,Asadi Majid4,Fernandez Julie1,Gholampour Seifollah1ORCID

Affiliation:

1. Department of Neurological Surgery, University of Chicago, Chicago, IL 60637, USA

2. Institute of Biomedical Systems of National Research University of Electronic Technology (MIET), 124498 Moscow, Russia

3. Institute of Bionic Technologies and Engineering of I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia

4. Northern Michigan University, Marquette, MI 49855, USA

Abstract

The present study aims to use enhanced ionic polymer–metal composites (IPMC) as an artificial muscle (a soft-active actuator) to restore eyelid movement of patients with ptosis. The previous eyelid movement mechanisms contained drawbacks, specifically in the lower eyelid. We used finite element analysis (FEA) to find the optimal mechanism among two different models (A and B). In addition to common electrodes of IPMC (gold and platinum), the bovine serum albumin (BSA) and microcrystalline cellulose (MCC) polymers, with optimal weight percentages of carbon nanotube (CNT) nanofiller, were also utilized as non-metallic electrodes to improve the efficiency of the IPMC actuator. In both models, IPMC with nanocomposite electrodes had higher efficiency as compared to the metallic electrodes. In model A, which moved eyelids indirectly, IPMC with MCC-CNT electrode generated a higher force (25.4%) and less stress (5.9 times) as compared to IPMC with BSA-CNT electrode. However, the use of model A (even with IPMCs) with nanocomposite electrodes can have limitations such as possible malposition issues in the eyelids (especially lower). IPMC with MCC-CNT nanocomposite electrode under model B, which moved eyelids directly, was the most efficient option to restore eyelid movement. It led to higher displacements and lower mechanical stress damage as compared to the BSA-CNT. This finding may provide surgeons with valuable data to open a window in the treatment of patients with ptosis.

Funder

Margaret Hackett Family Program

Publisher

MDPI AG

Subject

General Materials Science,General Chemical Engineering

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