Biodegradable Magnesium Alloys for Personalised Temporary Implants

Author:

Hendea Radu Emil1,Raducanu Doina2,Claver Adrián3ORCID,García José Antonio3ORCID,Cojocaru Vasile Danut2ORCID,Nocivin Anna4ORCID,Stanciu Doina5ORCID,Serban Nicolae2ORCID,Ivanescu Steliana5,Trisca-Rusu Corneliu6,Campian Radu Septimiu1

Affiliation:

1. Department of Oral Rehabilitation, Faculty of Dental Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania

2. Department of Metallic Materials Processing and Ecometallurgy, University Politehnica of Bucharest, 060042 Bucharest, Romania

3. Institute for Advanced Materials and Mathematics (INAMAT2), Universidad Pública de Navarra (UPNA), 31006 Pamplona, Spain

4. Faculty of Mechanical, Industrial and Maritime Engineering, OVIDIUS University of Constanta, 900527 Constanța, Romania

5. Zircon Dent SRL, 400690 Cluj-Napoca, Romania

6. National Institute for Research and Development in Micro-Technologies, 077190 Bucharest, Romania

Abstract

The objective of this experimental work was to examine and characterise the route for obtaining demonstrative temporary biodegradable personalised implants from the Mg alloy Mg-10Zn-0.5Zr-0.8Ca (wt.%). This studied Mg alloy was obtained in its powder state using the mechanical alloying method, with shape and size characteristics suitable for ensuing 3D additive manufacturing using the SLM (selective laser melting) procedure. The SLM procedure was applied to various processing parameters. All obtained samples were characterised microstructurally (using XRD—X-ray diffraction, and SEM—scanning electron microscopy); mechanically, by applying a compression test; and, finally, from a corrosion resistance viewpoint. Using the optimal test processing parameters, a few demonstrative temporary implants of small dimensions were made via the SLM method. Our conclusion is that mechanical alloying combined with SLM processing has good potential to manage 3D additive manufacturing for personalised temporary biodegradable implants of magnesium alloys. The compression tests show results closer to those of human bones compared to other potential metallic alloys. The applied corrosion test shows result comparable with that of the commercial magnesium alloy ZK60.

Funder

Romanian National Authority for Scientific Research, CCCDI–UEFISCDI

Gobierno de Navarra—Departamento de Desarrollo Económico

Publisher

MDPI AG

Subject

Biomedical Engineering,Biomaterials

Reference70 articles.

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4. Paiva, J.C.C., Oliveira, L., Vaz, M.F., and Costa-de-Oliveira, S. (2022). Biodegradable Bone Implants as a New Hope to Reduce Device-Associated Infections—A Systematic Review. Bioengineering, 9.

5. (2023, April 06). Orthopedic Implants Market Size, Share, Trends Analysis Report by Product (Hip Implants, Knee Implants, Spinal Implants, Craniomaxillofacial Implants), by Region, and Segment Forecasts 2023–2030, Report ID: GVR-1-68038-020-0. Available online: https://www.grandviewresearch.com/industry-analysis/orthopedic-implants-market.

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