The Role of Vitamin D in the Treatment of Carpal Tunnel Syndrome: Clinical and Electroneuromyographic Responses

Author:

Andrade Antônio Vicente D.1,Martins Dallianny G. S.1ORCID,Rocha Gabriel S.2ORCID,Damasceno Gustavo S.1,Gomes Francisca T. S.1,Albuquerque Yasmin P. F.1,Melo Paloma K. M.1,Freire Marco A. M.2ORCID,Araújo Dayane P.1,Oliveira Lucidio C.1,Guzen Fausto P.1,Morais Paulo L. A. G.1,Cavalcanti José R. L. P.1ORCID

Affiliation:

1. Laboratory of Experimental Neurology, Department of Biomedical Sciences, State University of Rio Grande do Norte, Mossoró, RN 59607-360, Brazil

2. Behavioural and Evolutionary Neurobiology Laboratory, Federal University of Sergipe, Itabaiana, SE 49500-000, Brazil

Abstract

Carpal tunnel syndrome (CTS) is the most common cause of peripheral compressive neuropathy and consists of compression of the median nerve in the wrist. Although there are several etiologies, idiopathic is the most prevalent origin, and among the forms of treatment for CTS, conservative is the most indicated. However, despite the high prevalence in and impact of this syndrome on the healthcare system, there are still controversies regarding the best therapeutic approach for patients. Therefore, noting that some studies point to vitamin D deficiency as an independent risk factor, which increases the symptoms of the syndrome, this study evaluated the role of vitamin D supplementation and its influence on pain control, physical examination and response electroneuromyography to conservative treatment of carpal tunnel syndrome. For this, the sample consisted of 14 patients diagnosed with CTS and hypovitaminosis D, who were allocated into two groups. The control group received corticosteroid treatment, while the experimental group received corticosteroid treatment associated with vitamin D. Thus, from this study, it can be concluded that patients who received vitamin D, when compared to those who did not receive it, showed improvement in the degree of pain intensity, a reduction in symptom severity and an improvement in some electroneuromyographic parameters.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

o Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

MDPI AG

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