Nomogram and Risk Calculator for Postoperative Tracheostomy after Heart Valve Surgery

Author:

Ding Xiangchao12,Sun Bing3,Liu Liang4,Lei Yuan5,Su Yunshu1

Affiliation:

1. Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan 430064, China

2. Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, China

3. Wuhan Third Hospital (Tongren Hospital of Wuhan University), Wuhan 430064, China

4. Department of Cardiovascular Surgery, Renmin Hospital of Wuhan University, Wuhan 430064, China

5. Department of Gerontology, Renmin Hospital of Wuhan University, Wuhan 430064, China

Abstract

Postoperative tracheostomy (POT) is an important indicator of critical illness, associated with poorer prognoses and increased medical burdens. However, studies on POTs after heart valve surgery (HVS) have not been reported. The objectives of this study were first to identify the risk factors and develop a risk prediction model for POTs after HVS, and second to clarify the relationship between POTs and clinical outcomes. Consecutive adults undergoing HVS from January 2016 to December 2019 in a single cardiovascular center were enrolled, and a POT was performed in 1.8% of the included patients (68/3853). Compared to patients without POTs, the patients with POTs had higher rates of readmission to the ICU and in-hospital mortality, as well as longer ICU and hospital stays. Five factors were identified to be significantly associated with POTs after HVS by our multivariate analysis, including age, diabetes mellitus, pulmonary edema, intraoperative transfusion of red blood cells, and surgical types. A nomogram and a risk calculator were constructed based on the five factors, showing excellent discrimination, calibration, and clinical utility. Three risk intervals were defined as low-, medium-, and high-risk groups according to the nomogram and clinical practice. The findings of this study may be helpful for early risk assessment and perioperative management.

Funder

Hubei Key Laboratory of Wuhan University

Fundamental Research Funds for the Central Universities

Publisher

MDPI AG

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

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