Bilateral Renal Auto-Transplantation for Retroperitoneal Sarcomas: Is It Underutilized?

Author:

Robinson Tyler P.1,Milgrom Daniel P.12,Nagaraju Santosh13,Goggins William C.1,Samy Kannan P.14,Koniaris Leonidas G.15

Affiliation:

1. Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA

2. Providence Saint John’s Cancer Institute, Santa Monica, CA 90404, USA

3. Renal Transplant Division, Charleston Area Medical Center, Charleston, WV 25301, USA

4. Department of Surgery, Duke University Medical Center, Durham, NC 27707, USA

5. Department of Surgery, Oregon Health and Science University, Portland, OR 97239, USA

Abstract

Sarcomas are a rare tumor of mesenchymal origin. The liposarcoma is the most common sarcoma of the retroperitoneum. Liposarcomas are typically low grade, and present at an advanced stage and a large size. We report a case of a large retroperitoneal liposarcoma, approximately 50 kg, encasing both kidneys, which was managed via a two-stage resection and staged renal auto-transplantation into the intra-peritoneal pelvis. The patient maintained normal renal function throughout, and remains disease free two years post-resection. Renal auto-transplantation with pelvic placement may facilitate improved margin-free resection. Renal relocation may allow the use of curative-intent ablative therapies such as radiofrequency ablation and radiation in cases of retroperitoneal recurrence.

Funder

National Institute of General Medical Sciences

National Cancer Institute

Publisher

MDPI AG

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