Key Considerations for the Treatment of Advanced Breast Cancer in Older Adults: An Expert Consensus of the Canadian Treatment Landscape

Author:

Jackson Emily B.12ORCID,Curry Lauren12,Mariano Caroline12,Hsu Tina34,Cook Sarah56,Pezo Rossanna C.78,Savard Marie-France34ORCID,Desautels Danielle N.910,Leblanc Dominique11,Gelmon Karen A.12

Affiliation:

1. BC Cancer Vancouver Centre, 600 West 10th Avenue, Vancouver, BC V5Z 4E6, Canada

2. Department of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada

3. The Ottawa Hospital Cancer Centre, Ottawa, ON K1H 8L6, Canada

4. Department of Medicine, University of Ottawa, Ottawa, ON K1H 8L6, Canada

5. Tom Baker Cancer Centre, Calgary, AB T2N 4N2, Canada

6. Department of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada

7. Sunnybrook Odette Cancer Centre, Toronto, ON M4N 3M5, Canada

8. Department of Medicine, Division of Medical Oncology, University of Toronto, Toronto, ON M5S 1A1, Canada

9. Department of Internal Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3E 3P4, Canada

10. Paul Albrechtsen Research Institute, CancerCare Manitoba, Winnipeg, MB R3E 0V9, Canada

11. Centre Hospitalier Universitaire de Québec, Université Laval, Québec, QC G1V 0A6, Canada

Abstract

The prevalence of breast cancer amongst older adults in Canada is increasing. This patient population faces unique challenges in the management of breast cancer, as older adults often have distinct biological, psychosocial, and treatment-related considerations. This paper presents an expert consensus of the Canadian treatment landscape, focusing on key considerations for optimizing selection of systemic therapy for advanced breast cancer in older adults. This paper aims to provide evidence-based recommendations and practical guidance for healthcare professionals involved in the care of older adults with breast cancer. By recognizing and addressing the specific needs of older adults, healthcare providers can optimize treatment outcomes and improve the overall quality of care for this population.

Publisher

MDPI AG

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