Demographic Analysis of Cancer Research Priorities and Treatment Correlations

Author:

Horgan Denis12ORCID,Van den Bulcke Marc3,Malapelle Umberto4ORCID,Normanno Nicola5ORCID,Capoluongo Ettore D.67,Prelaj Arsela8ORCID,Rizzari Carmelo9ORCID,Stathopoulou Aliki10,Singh Jaya1,Kozaric Marta1,Dube France11,Ottaviano Manuel12,Boccia Stefania1314ORCID,Pravettoni Gabriella1516,Cattaneo Ivana17,Malats Núria18ORCID,Buettner Reinhard19ORCID,Lekadir Karim20,de Lorenzo Francesco10,Alix-Panabieres Catherine21ORCID,Badreh Sara22,Solary Eric232425ORCID,De Maria Ruggero26,Hofman Paul27ORCID

Affiliation:

1. European Alliance for Personalised Medicine, 1040 Brussels, Belgium

2. Department of Molecular and Cellular Engineering, Jacob Institute of Biotechnology and Bioengineering, Faculty of Engineering and Technology, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj 211007, India

3. Belgian Cancer Centre, Sciensano, 1050 Brussels, Belgium

4. Department of Public Health, University Federico II of Naples, 80138 Naples, Italy

5. Istituto Nazionale Tumori “Fondazione G. Pascale”—IRCCS, 80131 Naples, Italy

6. Department of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II, 80138 Naples, Italy

7. Department of Clinical Pathology, Azienda Ospedaliera San Giovanni Addolorata, Via Amba Aradam 8, 00184 Rome, Italy

8. Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale Tumori, 20133 Milan, Italy

9. Unità di Ematologia Pediatrica, Fondazione MBBM, Università di Milano-Bicocca, 20126 Monza, Italy

10. European Cancer Patient Coalition, 1000 Brussels, Belgium

11. Astra Zeneca, Concord Pike, Wilmington, DE 19803, USA

12. Departamento de Tecnología Fotónica y Bioingeniería, Universidad Politècnica de Madrid, 28040 Madrid, Spain

13. Section of Hygiene, Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, 20123 Rome, Italy

14. Departments of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy

15. Department of Oncology and Hemato-Oncology, University of Milan, 20122 Milan, Italy

16. Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology (IEO) IRCCS, 20139 Milan, Italy

17. Novartis Farma SpA, 21042 Origgio, Italy

18. Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain

19. Lung Cancer Group Cologne, Institute of Pathology, Center for Integrated Oncology Cologne/Bonn, University Hospital Cologne, 50937 Cologne, Germany

20. Artificial Intelligence in Medicine Lab (BCN-AIM), Universitat de Barcelona, 08007 Barcelona, Spain

21. Laboratory of Rare Human Circulating Cells, University Medical Center of Montpellier, 34093 Montpellier, France

22. Cancer Childhood International, 1200 Vienna, Austria

23. INSERM U1287, Gustave Roussy Cancer Campus, 94805 Paris, France

24. Faculty of Medicine, Université Paris-Sud, 91405 Le Kremlin-Bicêtre, Île-de-France, France

25. Department of Hematology, Gustave Roussy Cancer Campus, 94805 Paris, France

26. Institute of General Pathology, Catholic University of the Sacred Heart, 20123 Rome, Italy

27. IHU RespirERA, FHU OncoAge, Laboratory of Clinical and Experimental Pathology, Pasteur Hospital, Université Côte d’Azur, 06000 Nice, France

Abstract

Understanding the diversity in cancer research priorities and the correlations among different treatment modalities is essential to address the evolving landscape of oncology. This study, conducted in collaboration with the European Cancer Patient Coalition (ECPC) and Childhood Cancer International-Europe (CCI-E) as part of the “UNCAN.eu” initiative, analyzed data from a comprehensive survey to explore the complex interplay of demographics, time since cancer diagnosis, and types of treatments received. Demographic analysis revealed intriguing trends, highlighting the importance of tailoring cancer research efforts to specific age groups and genders. Individuals aged 45–69 exhibited highly aligned research priorities, emphasizing the need to address the unique concerns of middle-aged and older populations. In contrast, patients over 70 years demonstrated a divergence in research priorities, underscoring the importance of recognising the distinct needs of older individuals in cancer research. The analysis of correlations among different types of cancer treatments underscored the multidisciplinary approach to cancer care, with surgery, radiotherapy, chemotherapy, precision therapy, and biological therapies playing integral roles. These findings support the need for personalized and combined treatment strategies to achieve optimal outcomes. In conclusion, this study provides valuable insights into the complexity of cancer research priorities and treatment correlations in a European context. It emphasizes the importance of a multifaceted, patient-centred approach to cancer research and treatment, highlighting the need for ongoing support, adaptation, and collaboration to address the ever-changing landscape of oncology.

Funder

Reducing Disparities Across the European Union

CAN.HEAL project

Publisher

MDPI AG

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