Breaking Down Barriers to Detection and Care in Early-Age-Onset Colorectal Cancer in Canada

Author:

Raphael Michael J.1,Wildgoose Petra1,Servidio-Italiano Filomena2,De Vera Mary A.3ORCID,Brenner Darren4,D’Angelo Monika Slovinec2ORCID,McGee Robin5,Berry Scott6,Wong Clarence7ORCID,Gill Sharlene8ORCID

Affiliation:

1. Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada

2. Colorectal Cancer Resource & Action Network (CCRAN), Toronto, ON M4W 3E2, Canada

3. Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC V6T 1Z3, Canada

4. Department of Community Health Sciences, University of Calgary, Calgary, AB T2N 4N1, Canada

5. Independent Researcher, Port Williams, NS, Canada

6. Department of Oncology, Carlo Fidani Peel Regional Cancer Centre, Mississauga, ON L5M 7S4, Canada

7. Division of Gastroenterology, University of Alberta, Edmonton, AB T6G 2X8, Canada

8. Division of Medical Oncology, BC Cancer, University of British Columbia, Vancouver, BC V5Z 4E6, Canada

Abstract

The second Early-Age-Onset Colorectal Cancer Symposium, convened in October 2022, sought solutions to the barriers to early detection and care for colorectal cancer in Canada. This meeting built on a previous symposium, held in 2021 and reported in this journal. Early-age-onset colorectal cancer (EAOCRC) affects increasing numbers of people under the age of 50 in Canada and throughout the developed world. Two main themes emerged from the meeting: the importance of timely detection, and the need for a tailored approach to the care of EAOCRC. Early detection is crucial, especially in light of the later stage at diagnosis and unique tumour characteristics. Symposium participants were strongly in favour of reducing the age of eligibility for screening from 50 to 45, and promoting the development of non-invasive screening techniques such as testing for circulating tumour DNA and biomarkers. Leading approaches to care were described and discussed, which meet the unique treatment needs of younger CRC patients. Multidisciplinary practices within and outside Canada address such factors as fertility, family roles, education, careers and financial responsibilities. These models can be applied in treatment centres across the country.

Publisher

MDPI AG

Reference41 articles.

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2. Canadian Cancer Statistics Advisory Committee, Canadian Cancer Society, Statistics Canada, and Public Health Agency of Canada (2021). Canadian Cancer Statistics 2021, Canadian Cancer Society. Available online: https://cdn.cancer.ca/-/media/files/research/cancer-statistics/2021-statistics/2021-pdf-en-final.pdf.

3. Changes in colorectal cancer incidence rates in young and older adults in the United States: What does it tell us about screening;Austin;Cancer Causes Control,2014

4. Canadian Task Force on Preventive Health Care (2016). Recommendations on screening for colorectal cancer in primary care. CMAJ, 188, 340–348.

5. Canadian Partnership Against Cancer (2019). Canadian Strategy for Cancer Control 2019–2029, Canadian Partnership Against Cancer. Available online: https://www.partnershipagainstcancer.ca/cancer-strategy/.

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