The Constrained Disorder Principle Accounts for the Variability That Characterizes Breathing: A Method for Treating Chronic Respiratory Diseases and Improving Mechanical Ventilation

Author:

Adar Ofek12,Hollander Adi12,Ilan Yaron12ORCID

Affiliation:

1. Faculty of Medicine, Hebrew University, Jerusalem P.O. Box 1200, Israel

2. Department of Medicine, Hadassah Medical Center, Jerusalem P.O. Box 1200, Israel

Abstract

Variability characterizes breathing, cellular respiration, and the underlying quantum effects. Variability serves as a mechanism for coping with changing environments; however, this hypothesis does not explain why many of the variable phenomena of respiration manifest randomness. According to the constrained disorder principle (CDP), living organisms are defined by their inherent disorder bounded by variable boundaries. The present paper describes the mechanisms of breathing and cellular respiration, focusing on their inherent variability. It defines how the CDP accounts for the variability and randomness in breathing and respiration. It also provides a scheme for the potential role of respiration variability in the energy balance in biological systems. The paper describes the option of using CDP-based artificial intelligence platforms to augment the respiratory process’s efficiency, correct malfunctions, and treat disorders associated with the respiratory system.

Publisher

MDPI AG

Subject

Pulmonary and Respiratory Medicine

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