Differences in Troponin I and Troponin T Release in High-Performance Athletes Outside of Competition

Author:

Wuestenfeld Jan C.12ORCID,Kastner Tom12,Hesse Judith12,Fesseler Leon2,Frohberg Florian1,Rossbach Cornelius12,Wolfarth Bernd12ORCID

Affiliation:

1. Institute for Applied Training Science, Marschnerstrasse 29, 04109 Leipzig, Germany

2. Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Department of Sports Medicine, Charitéplatz 1, 10117 Berlin, Germany

Abstract

Troponin I and troponin T are critical biomarkers for myocardial infarction and damage and are pivotal in cardiological and laboratory diagnostics, including emergency settings. Rapid testing protocols have been developed for urgent care, particularly in emergency outpatient clinics. Studies indicate that strenuous physical activity can cause transient increases in these troponin levels, which are typically considered benign. This research focused on 219 elite athletes from national teams, evaluating their troponin I and T levels as part of routine sports medical exams, independent of competition-related physical stress. The results showed that 9.2% (18 athletes) had elevated troponin I levels above the reporting threshold, while their troponin T levels remained within the normal range. Conversely, only 0.9% (two athletes) had normal troponin I but raised troponin T levels, and 2.3% (five athletes) exhibited increases in both markers. No significant cardiovascular differences were noted between those with elevated troponin levels and those without. This study concludes that elevated troponin I is a common response to the intense physical training endured by high-performance endurance athletes, whereas troponin T elevation does not seem to be directly linked to physical exertion in this group. For cardiac assessments, particularly when ruling out cardiac damage in these athletes, troponin T might be a more reliable indicator than troponin I.

Funder

German Federal Ministry of the Interior and Community

Open Access Publication Fund of Charité—Universitätsmedizin Berlin

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

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