1. Department of Pharmacy (DIFAR), University of Genoa, Viale Cembrano 4, 16148 Genova, Italy
2. Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Largo Paolo Daneo, 16132 Genoa, Italy
3. UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy
4. Inter-University Center for the Promotion of the 3Rs Principles in Teaching & Research (Centro 3R), 56122 Pisa, Italy
5. Department of Experimental Medicine (DIMES), University of Genoa, Via Alberti L.B. 2, 16132 Genova, Italy
6. Institute of Biophysics, National Research Council (CNR), Via De Marini 6, 16149 Genoa, Italy
7. Department of Neurosciences, Experimental Neurology, and Leuven Brain Institute, KU Leuven-University of Leuven, 3000 Leuven, Belgium
8. VIB-Center for Brain & Disease Research, Laboratory of Neurobiology, 3000 Leuven, Belgium
9. Ionis Pharmaceuticals, Carlsbad, CA 92010, USA
10. IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi 10, 16132 Genoa, Italy