Questions about Using the Induced Membrane Technique to Manage Cases of Congenital Tibial Pseudarthrosis-Reference-Cited by-同舟云学术

Questions about Using the Induced Membrane Technique to Manage Cases of Congenital Tibial Pseudarthrosis

Published:2023-07-24 Issue:14 Volume:12 Page:1918
ISSN:2073-4409
Container-title:Cells
language:en
Short-container-title:Cells

Author:

Klein Céline¹²³^ORCID,Gindraux Florelle⁴⁵^ORCID,Masquelet Alain-Charles⁶,Mentaverri Romuald²⁴⁵⁶⁷,Gouron Richard¹

Affiliation:

1. Department of Paediatric Orthopaedic Surgery, Amiens University Hospital, Jules Verne University of Picardie, F-80054 Amiens, France

2. MP3CV-EA7517, CURS–Amiens University Medical Center, Jules Verne University of Picardie, F-80025 Amiens, France

3. Service D’orthopédie et Traumatologie Pédiatrique, CHU Amiens-Picardie, F-80054 Amiens CEDEX 1, France

4. CHU Besançon, Service de Chirurgie Orthopédique, Traumatologique et Plastique, F-25000 Besançon, France

5. Laboratoire de Nanomédecine, Imagerie, Université de Franche-Comté, Thérapeutique EA 4662 (LNIT), F-25000 Besançon, France

6. Hôpital Saint Antoine, Sorbonne Université, F-75006 Paris, France

7. Department of Biochemistry and Endocrine Biology, Amiens University Medical Center, Jules Verne University of Picardie, F-80025 Amiens, France

Abstract

The induced membrane technique is an innovative approach for repairing critical bone defects and has been applied recently in patients with congenital pseudarthrosis of the tibia (CPT). CPT is frequently associated with neurofibromatosis type 1 (NF1). Here, we briefly describe the clinical results of the induced membrane technique in NF1-deficient patients with CPT and in an animal model of CPT. Furthermore, we discuss the hypotheses used to explain inconsistent outcomes for the induced membrane technique in CPT–especially when associated with NF1.

Publisher

MDPI AG

Subject

General Medicine

Link

https://www.mdpi.com/2073-4409/12/14/1918/pdf

Reference41 articles.

1. Neurofibromatosis Update;Crawford;J. Pediatr. Orthop.,2006

2. Pathology and Natural History of Congenital Pseudarthrosis of the Tibia;Boyd;Clin. Orthop.,1982

3. Biologic Characteristics of Fibrous Hamartoma from Congenital Pseudarthrosis of the Tibia Associated with Neurofibromatosis Type 1;Cho;J. Bone Jt. Surg. Am.,2008

4. Vascular Changes in the Periosteum of Congenital Pseudarthrosis of the Tibia;Senderek;Pathol. Res. Pract.,2005

5. Congenital Pseudarthrosis of the Tibia: History, Etiology, Classification, and Epidemiologic Data;Hefti;J. Pediatr. Orthop. Part B,2000