Upconversion-Powered Photoelectrochemical Bioanalysis for DNA Sensing-Reference-Cited by-同舟云学术

Upconversion-Powered Photoelectrochemical Bioanalysis for DNA Sensing

Published:2024-01-24 Issue:3 Volume:24 Page:773
ISSN:1424-8220
Container-title:Sensors
language:en
Short-container-title:Sensors

Author:

Liu Hong¹,Wei Weiwei¹,Song Jiajun¹,Hu Jin¹,Wang Zhezhe²,Lin Peng¹

Affiliation:

1. Shenzhen Key Laboratory of Special Functional Materials & Guangdong Research Center for Interfacial Engineering of Functional Materials, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China

2. Fujian Provincial Key Laboratory of Quantum Manipulation and New Energy Materials, College of Physics and Energy, Fujian Normal University, Fuzhou 350117, China

Abstract

In this work, we report a new concept of upconversion-powered photoelectrochemical (PEC) bioanalysis. The proof-of-concept involves a PEC bionanosystem comprising a NaYF4:Yb,Tm@NaYF4 upconversion nanoparticles (UCNPs) reporter, which is confined by DNA hybridization on a CdS quantum dots (QDs)/indium tin oxide (ITO) photoelectrode. The CdS QD-modified ITO electrode was powered by upconversion absorption together with energy transfer effect through UCNPs for a stable photocurrent generation. By measuring the photocurrent change, the target DNA could be detected in a specific and sensitive way with a wide linear range from 10 pM to 1 μM and a low detection limit of 0.1 pM. This work exploited the use of UCNPs as signal reporters and realized upconversion-powered PEC bioanalysis. Given the diversity of UCNPs, we believe it will offer a new perspective for the development of advanced upconversion-powered PEC bioanalysis.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Shenzhen Science and Technology Program

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Biochemistry,Instrumentation,Atomic and Molecular Physics, and Optics,Analytical Chemistry

Link

https://www.mdpi.com/1424-8220/24/3/773/pdf

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