Abstract
The development and implementation of the approaches of personalized medicine for disease prevention are still at infancy, although preventive activities in healthcare represent a key pillar to guarantee health system sustainability. There is an increasing interest in finding informative markers that indicate the disease risk before the manifestation of the disease (primary prevention) or for early disease detection (secondary prevention). Recently, the systematic collection and study of clinical phenotypes and biomarkers consented to the advance of Rehabilomics in tertiary prevention. It consents to identify relevant molecular and physiological factors that can be linked to plasticity, treatment response, and natural recovery. Implementation of these approaches would open avenues to identify people at high risk and enable new preventive lifestyle interventions or early treatments targeted to their individual genomic profile, personalizing prevention and rehabilitation. The integration of personalized medicine into prevention may benefit citizens, patients, healthcare professionals, healthcare authorities, and industry, and ultimately will seek to contribute to better health and quality of life for Europe’s citizens.
Reference56 articles.
1. Population Structure and Ageing—Statistics Explained,2016
2. How Can Health Systems Respond to Population Ageing?https://researchonline.lshtm.ac.uk/id/eprint/4807/1/E92560.pdf
3. State of Health in the EU’s 2019 Companion Reporthttps://ec.europa.eu/health/sites/health/files/state/docs/2019_companion_en.pdf
4. How to Integrate Personalized Medicine into Prevention? Recommendations from the Personalized Prevention of Chronic Diseases (PRECeDI) Consortium
5. Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts
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