Factors Associated with Increased Burden of Caregivers of People with Dementia with Lewy Bodies

Author:

Toya Shunji1,Hashimoto Mamoru23,Manabe Yuta4,Yamakage Hajime5,Ikeda Manabu2

Affiliation:

1. Medical Science, Sumitomo Pharma Co., Ltd., Tokyo 103-6012, Japan

2. Department of Psychiatry, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan

3. Department of Neuropsychiatry, Kindai University Faculty of Medicine, Osakasayama 577-8502, Japan

4. Department of Advanced Clinical Medicine, Division of Dementia and Geriatric Medicine, Kanagawa Dental University School of Dentistry, Yokosuka 238-0003, Japan

5. Insight Clinical Development Group, 3H Medi Solution Co., Ltd., Tokyo 171-0022, Japan

Abstract

The burden of caregivers of people with dementia with Lewy bodies (DLB) is high; however, factors related to their caregiving burden are not fully clarified. We herein investigated factors associated with increasing caregiver burden for caregivers of people with DLB. To explore factors associated with caregiver burden, a linear regression analysis was conducted using the J-ZBI_8 total score as the dependent variable and a total of 36 factors as independent variables. This analysis included 252 pairs of people with DLB and their caregivers. Caregivers’ mean J-ZBI_8 was 8.4, indicating that caregiver burden was generally high. First, we identified 20 factors associated with caregiver burden in univariable analysis. Finally, multivariable analysis found three significant factors: irritability (β = 0.208, p < 0.001), use of “short stay” or “small-scale, multifunctional home care” (β = 0.208, p < 0.001), and nighttime behavior (β = 0.138, p = 0.020) were significantly associated with J-ZBI_8 total scores. Irritability and nighttime behavior were found to be contributing factors to caregiver burden. High caregiver burden among caregivers of people with DLB may result in the use of social services providing overnight stays, but to what extent such services reduce caregiver burden is unknown.

Funder

Sumitomo Pharma Co., Ltd.

Publisher

MDPI AG

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