Lower Extremity Amputation and Peripheral Revascularisation Rates in Romania and Their Relationship with Comorbidities and Vascular Care

Author:

Ionac Stefan1ORCID,Rogers Steven K.23ORCID,Bondor Cosmina I.4,Bowling Frank L.23,Dragoi Iulia Iovanca1,Ionac Mihai5ORCID

Affiliation:

1. CerVasc, Vascular and Endovascular Surgery Research Center, Faculty of Medicine, Victor Babes University of Medicine and Pharmacy, Piata Eftimie Murgu 2, 300041 Timisoara, Romania

2. School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Oxford Road, Manchester M13 9WL, UK

3. Manchester Academic Vascular Research and Innovation Centre (MAVRIC), Manchester University NHS Foundation Trust, Oxford Road, Manchester M13 9WL, UK

4. Department of Medical Informatics and Biostatistics, Iuliu Hațeganu University of Medicine and Pharmacy, 6 Pasteur Street, 400349 Cluj-Napoca, Romania

5. Clinic of Vascular Surgery, Victor Babes University of Medicine and Pharmacy, Piata Eftimie Murgu 2, 300041 Timisoara, Romania

Abstract

(1) Background: This retrospective Romanian study aimed to calculate the rate of, and comparison between, amputation and revascularisation for patients with either cardiovascular or diabetic comorbidities. (2) Materials: In our hospital-based database, we analysed patient-level data from a series of 61 hospitals for 2019, which covers 44.9% of the amputation patients for that year. The national database is compiled by the national houses of insurance and was used to follow amputations and revascularisations between 2016 and 2021. (3) Results: During the six-year period, the mean number of amputations and revascularisations was 72.4 per 100,000 inhabitants per year for both groups. In this period, a decline in open-surgical revascularisation was observed from 58.3% to 47.5% in all interventions but was not statistically significant (r = −0.20, p = 0.70). The mean age of patients with amputation (hospital-based database) was 67 years. Of these patients, only 5.1% underwent revascularisation in the same hospital prior to amputation. The most common comorbidities in those undergoing amputations were peripheral arterial disease (76.8%), diabetes (60.8%), and arterial hypertension (53.5%). Most amputations were undertaken by general surgeons (73.0%) and only a small number of patients were treated by vascular surgeons (17.4%). (4) Conclusions: The signal from our data indicates that Romanian patients probably have a high risk of amputation > 5 years earlier than Western European countries, such as Denmark, Finland, and Germany. The prevalence of revascularisations in Romania is 64% lower than in the Western European countries.

Funder

The Romanian Society of Vascular Surgery

Publisher

MDPI AG

Subject

General Medicine

Reference25 articles.

1. Epidemiology of peripheral artery disease;Criqui;Circ. Res.,2015

2. Major Amputation Rates in Patients with Peripheral Arterial Disease Aged 50 Years and Over in Denmark during the period 1997–2014 and their Relationship with Demographics, Risk Factors, and Vascular Services;Londero;Eur. J. Vasc. Endovasc. Surg.,2019

3. Critical limb ischemia: A global epidemic. A critical analysis of current treatment unmasks the clinical and economic costs of CLI;Allie;EuroIntervention,2005

4. Mortality After Nontraumatic Major Amputation Among Patients with Diabetes and Peripheral Vascular Disease: A Systematic Review;Thorud;J. Foot Ankle Surg.,2016

5. (2022, December 10). Available online: https://insse.ro/cms/sites/default/files/com_presa/com_pdf/poprez_ian2022r_0.pdf.

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