Advancements in Aerogel Technology for Antimicrobial Therapy: A Review

Author:

Croitoru George-Alexandru1,Pîrvulescu Diana-Cristina2,Niculescu Adelina-Gabriela23ORCID,Rădulescu Marius2,Grumezescu Alexandru Mihai23ORCID,Nicolae Carmen-Larisa1

Affiliation:

1. Faculty of Dental Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania

2. Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania

3. Research Institute of the University of Bucharest—ICUB, University of Bucharest, 050657 Bucharest, Romania

Abstract

This paper explores the latest advancements in aerogel technology for antimicrobial therapy, revealing their interesting capacity that could improve the current medical approaches for antimicrobial treatments. Aerogels are attractive matrices because they can have an antimicrobial effect on their own, but they can also provide efficient delivery of antimicrobial compounds. Their interesting properties, such as high porosity, ultra-lightweight, and large surface area, make them suitable for such applications. The fundamentals of aerogels and mechanisms of action are discussed. The paper also highlights aerogels’ importance in addressing current pressing challenges related to infection management, like the limited drug delivery alternatives and growing resistance to antimicrobial agents. It also covers the potential applications of aerogels in antimicrobial therapy and their possible limitations.

Publisher

MDPI AG

Reference130 articles.

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