Organogel of Acai Oil in Cosmetics: Microstructure, Stability, Rheology and Mechanical Properties

Author:

Sanches Suellen Christtine da Costa1ORCID,Ré Maria Inês2,Silva-Júnior José Otávio Carréra3ORCID,Ribeiro-Costa Roseane Maria1

Affiliation:

1. Laboratory of Pharmaceutical Nanotechnology, College of Pharmacy, Federal University of Pará, Belém 66075-110, Brazil

2. IMT Mines Albi-Carmaux, CNRS UMR 5302, Centre RAPSODEE, Campus Jarlard, Université de Toulouse, CEDEX 09, 81013 Albi, France

3. Laboratory R&D Pharmaceutical and Cosmetic, Faculty of Pharmaceutical Sciences, Federal University of Pará, Belém 66075-110, Brazil

Abstract

Organogel (OG) is a semi-solid material composed of gelling molecules organized in the presence of an appropriate organic solvent, through physical or chemical interactions, in a continuous net. This investigation aimed at preparing and characterizing an organogel from acai oil with hyaluronic acid (HA) structured by 12-hydroxystearic acid (12-HSA), aiming at topical anti-aging application. Organogels containing or not containing HA were analyzed by Fourier-transform Infrared Spectroscopy, polarized light optical microscopy, thermal analysis, texture analysis, rheology, HA quantification and oxidative stability. The organogel containing hyaluronic acid (OG + HA) has a spherulitic texture morphology with a net-like structure and absorption bands that evidenced the presence of HA in the three-dimensional net of organogel. The thermal analysis confirmed the gelation and the insertion of HA, as well as a good thermal stability, which is also confirmed by the study of oxidative stability carried out under different temperature conditions for 90 days. The texture and rheology studies indicated a viscoelastic behavior. HA quantification shows the efficiency of the HA cross-linking process in the three-dimensional net of organogel with 11.22 µg/mL for cross-linked HA. Thus, it is concluded that OG + HA shows potentially promising physicochemical characteristics for the development of a cosmetic system.

Funder

PROPESP/UFPA

Coordenação de Aperfeiçoamento Pessoal (CAPES) a 001

Publisher

MDPI AG

Subject

Polymers and Plastics,Organic Chemistry,Biomaterials,Bioengineering

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