Cryosurgery for Basal Cell Skin Cancer of the Head: 15 Years of Experience

Author:

Pustinsky Ilya12,Dvornikov Anton1,Kiva Ekaterina3,Chulkova Svetlana12ORCID,Egorova Angelina1ORCID,Gladilina Irina1,Peterson Sergey1,Lepkova Nataly1,Grishchenko Natalya2,Galaeva Zamira1,Baisova Aigul1,Kalinin Sergey1

Affiliation:

1. Federal State Autonomous Educational Institution of Higher Education «N.I. Pirogov Russian National Research Medical University» of the Ministry of Health of the Russian Federation, 117997 Moscow, Russia

2. FSBI “N.N. Blokhin Russian Cancer Research Center” Ministry of Health of the Russian Federation, 115478 Moscow, Russia

3. LCR Center Traditional Medicine “Five Elements”, 140104 Moscow, Russia

Abstract

The clinical relevance of head and neck (H&N) tumors is related to the potential disfiguration of anatomical structures (by the tumor or surgical intervention), defining patients’ individual features and emotional expression, loss or restraint of vital structures functions, and untoward socio-economic sequelae. This study is aimed to improve clinical outcomes of cryosurgery in patients with H&N basal cell skin cancer by refining the indications for cryosurgical treatment. In this study, cryosurgery was used in 234 patients with different stages of cutaneous basal cell carcinoma (BCC) of the head, including 101 patients with T1 tumors, 86—with T2, 5—T3, and 42 patients with tumors relapsing after failure of preceding various treatment modalities. Post-cryosurgery recurrence rate in patients with stage I BCC was 2.7%, with stage II tumors—5.6% and 34.9%—in patients with recurred tumors. Re-recurrence after cryoablation of recurrent tumors correlated with the tumor baseline size. The best aesthetic and long-term clinical results were documented in patients with lesions <1 cm in size with clear boundaries. Thus, cryosurgery is the method of choice for the majority of stage I basal cell carcinomas of the head. For patients with advanced and recurrent skin cancer, cryosurgery is relevant in rare cases selected according to refined indications.

Publisher

MDPI AG

Subject

Paleontology,Space and Planetary Science,General Biochemistry, Genetics and Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference37 articles.

1. Nonmelanoma skin cancer;Dubas;Facial Plast. Surg. Clin. N. Am.,2013

2. Skin Cancer Epidemiology, Detection, and Management;Gandhi;Med. Clin. N. Am.,2015

3. Diagnosis and treatment of Basal cell and squamous cell carcinoma;Firnhaber;Am. Fam. Physician,2012

4. Epidemiological trends in skin cancer;Apalla;Dermatol. Pract. Concept.,2017

5. Kaprin, A.D., Starinsky, V.V., and Petrova, G.V. (2023, October 15). Malignant Neoplasms in Russia in 2020 (Morbidity and Mortality), Available online: https://hnj.science/wp-content/uploads/2020/06/1_2019.pdf.

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