4,5,6-Trichloropyrimidine-2-carboxamide-Reference-Cited by-同舟云学术

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4,5,6-Trichloropyrimidine-2-carboxamide

Published:2021-02-09 Issue:1 Volume:2021 Page:M1190
ISSN:1422-8599
Container-title:Molbank
language:en
Short-container-title:Molbank

Author:

Kalogirou Andreas S.^ORCID,Koutentis Panayiotis A.^ORCID

Abstract

Reaction of 4,5,6-trichloropyrimidine-2-carbonitrile (1) with concentrated sulfuric acid at ca. 20 °C gave 4,5,6-trichloropyrimidine-2-carboxamide (5) in 91% yield. The new compound was fully characterized by IR, MALDI-TOF, NMR and elemental analysis.

Funder

Cyprus Research Promotion Foundation

Publisher

MDPI AG

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://www.mdpi.com/1422-8599/2021/1/M1190/pdf

Reference13 articles.

1. Nucleic Acids: General Properties

2. Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

3. 4-Hydroxy-2-quinolones 144. Alkyl-, arylalkyl-, and arylamides of 2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid and their diuretic properties

4. Synthesis, Reactions, and Anti-inflammatory Activity of Heterocyclic Systems Fused to a Thiophene Moiety Using Citrazinic Acid As Synthon

5. Indeno[1,2-d]pyrimidin-4-yl-amines;Gorlitzer;Pharmazie,1997

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