Organic–Inorganic Nanocomposites of Aspergillus terreus Extract and Its Compounds with Antimicrobial Properties

Author:

Uras Ibrahim Seyda12ORCID,Karsli Baris3,Konuklugil Belma14,Ocsoy Ismail5,Demirbas Ayse3ORCID

Affiliation:

1. Department of Pharmacognosy, Faculty of Pharmacy, Ankara University, Ankara 06560, Turkey

2. Department of Pharmacognosy, Faculty of Pharmacy, Agri Ibrahim Cecen University, Agri 04100, Turkey

3. Department of Seafood Processing Technology, Faculty of Fisheries, Recep Tayyip Erdogan University, Rize 53100, Turkey

4. Department of Pharmacognosy, Faculty of Pharmacy, Lokman Hekim University, Ankara 06510, Turkey

5. Department of Analytical Chemistry, Faculty of Pharmacy, Erciyes University, Kayseri 38039, Turkey

Abstract

Due to its distinct, atypical features and possible applications, three-dimensional (3D) hierarchical nanoflowers have sparked considerable interest. Copper (II) ions were employed as inorganic components in this study, whereas various extracts from Aspergillus terreus and their extracted main components were used as organic components. Extracts from A. terreus and its isolated principal component molecules can first form complexes with copper ions, and these complexes subsequently become nucleation sites for primary copper phosphate crystals, showing interactions using an easy and successful self-assembly template synthesis technique. Therefore, the process results in the formation of 3D nanoflowers among the A. terreus extract and its remoted important additives in addition to copper ions, ensuing in a completely unique round flower-like shape containing loads of nanopetals under the most excellent conditions along with pH, attention of organic–inorganic additives, temperature, and the quantity of copper nitrate on nanoflower formation. Furthermore, A. terreus and its isolated major components, Cu3(PO4)2 nanoflowers, seemed to have a remarkable antibacterial effect. Our findings highlight the benefits of nanoflowers made with A. terreus and its isolated secondary metabolites of inorganic structures, which could be used in industrial biocatalysts, biosensors, and environmental chemistry.

Funder

Turkish Scientific and Technological Research Council

Publisher

MDPI AG

Subject

Management, Monitoring, Policy and Law,Renewable Energy, Sustainability and the Environment,Geography, Planning and Development,Building and Construction

Reference104 articles.

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