1. Institute for Theoretical Medicine, Inc., 26-1 Muraoka-Higashi 2-Chome, Fujisawa 251-0012, Japan
2. Department of Life Science Informatics and Data Science, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Friedrich-Hirzebruch-Allee 5/6, 53115 Bonn, Germany