Suicide by Pesticide (Phorate) Ingestion: Case Report and Review of Literature

Author:

Simonelli Angela,Carfora AnnaORCID,Basilicata Pascale,Liguori Bruno,Mascolo Pasquale,Policino Fabio,Niola Massimo,Campobasso Carlo PietroORCID

Abstract

It has been estimated that approximately one in seven of all global suicides is due to pesticide self-poisoning, mostly in rural areas of developing countries. Organophosphorus (OP) compounds are a group of pesticides exerting their toxicological effects through non-reversible inhibition of the enzyme acetylcholinesterase (AChE). Among these compounds, phorate (thimet) is one of the most dangerous compounds, the use of which is restricted in many countries. A case of intentional suicide after phorate ingestion in a 24-year-old Bengali male is described. This is the second case of suicidal ingestion of phorate reported in the forensic literature, and the first presenting complete toxicological findings.

Publisher

MDPI AG

Subject

Chemical Health and Safety,Health, Toxicology and Mutagenesis,Toxicology

Reference38 articles.

1. International Code of Conduct on the Distribution and Use of Pesticides,2005

2. Soil Chemistry of Pesticides;Drum,1980

3. Chemistry of Pesticides;Buchel,1980

4. A review on phorate persistence, toxicity and remediation by bacterial communities

5. Exposure to pesticides and the associated human health effects

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