Epidemiological Investigation: Important Measures for the Prevention and Control of COVID-19 Epidemic in China

Abstract

Based on China’s summary of three years of experience and measures in the prevention and control of the COVID-19 epidemic, we have built a COVID-19 prevention and control model integrating health and medical detection, big data information technology to track the trend of the epidemic throughout the whole process, isolation of key epidemic areas, and dynamic prevention and control management throughout the whole process. This model provides a simple, feasible, and theoretically reliable prevention and control model for future large-scale infectious disease prevention and control. The Lyapnov functional method is replaced by the global exponential attractor theory, which provides a new mathematical method for studying the global stability of the multi parameter, multi variable infectious disease prevention and control system. We extracted mathematical methods and models suitable for non-mathematical infectious disease researchers from profound and difficult to understand mathematical theories. Using the results of the global exponential Attractor theory obtained in this paper, we studied the global dynamics of the COVID-19 model with an epidemiological investigation. The results demonstrated that the non-constant disease-free equilibrium is globally asymptotically stable when λ*<0, and the COVID-19 epidemic is persisting uniformly when λ*>0. In order to understand the impact of the epidemiological investigation under different prevention and control stages in China, we compare the control effects of COVID-19 under different levels of epidemiological investigation policies. We visually demonstrate the global stability and global exponential attractiveness of the COVID-19 model with transferors between regions and epidemiological investigation in a temporal-spatial heterogeneous environment with the help of numerical simulations. We find that the epidemiological investigation really has a significant effect on the prevention and control of the epidemic situation, and we can also intuitively observe the relationship between the flow of people (including tourism, shopping, work and so on) and epidemiological investigation policies. Our model is adapted to different stages of prevention and control; the emergency “circuit breaker” mechanism of the model is also consistent with actual prevention and control.