Clinical Impact of Self-Recognition of Recurrent Acute Myocardial Infarction: From KRMI-RCC

Author:

Kim Kyehwan1ORCID,Kim Moojun1,Seo Chang-Ok1ORCID,Kim Hangyul12,Kim Hye Ree1ORCID,Kang Min Gyu12,Koh Jin-Sin12,Park Jeong Rang1,Kim Rock Bum2ORCID,Ryu Dong Ryeol3,Lee Jang Hoon4ORCID,Kim Moo Hyun5ORCID,Youn Tae-Jin6,Hyun Dae Woo7,Kim Shin-Jae8,Rhee Sang Jae9ORCID,Park Sang-Don10,Hong Young Joon11,Lee Jae-Geun12ORCID,Song Pil Sang13,Kim Sang Min14,Lee Seung Jin15,Hwang Jin-Yong12

Affiliation:

1. Division of Cardiology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Gyeongsang National University Hospital, Jinju 52727, Republic of Korea

2. Regional Cardiocerebrovascular Disease Center, Gyeongsang National University Hospital, Jinju 52727, Republic of Korea

3. Division of Cardiology, Department of Internal Medicine, Kangwon National University School of Medicine, 156 Baengnyeong-ro, Chuncheon 24289, Republic of Korea

4. Department of Internal Medicine, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Kyungpook National University, 807, Hoguk-ro, Buk-gu, Daegu 41404, Republic of Korea

5. Department of Cardiology, Dong-A University Hospital, 26, Daesingongwon-ro, Seo-gu, Busan 49201, Republic of Korea

6. Cardiovascular Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 173-82, Gumi-ro, Bundang-gu, Seongnam-si 13620, Republic of Korea

7. Department of Internal Medicine, Andong General Hospital, 11, Angsil-ro, Andong 36743, Republic of Korea

8. Division of Cardiology, Ulsan University Hospital, University of Ulsan College of Medicine, 171-19, Wolpyeong-ro, Nam-gu, Ulsan 44686, Republic of Korea

9. Regional Cardiocerebrovascular Center, Department of Cardiovascular Medicine, Wonkwang University Hospital, 33-13 Iksan-daero, Iksan 54536, Republic of Korea

10. Division of Cardiology, Department of Internal Medicine, Inha University Hospital, 27, Inhang-ro, Jung-gu, Incheon 22332, Republic of Korea

11. Division of Cardiology, Chonnam National University Hospital, 42, Jebong-ro, Dong-gu, Gwangju 61469, Republic of Korea

12. Division of Cardiology, Department of Internal Medicine, Jeju National University School of Medicine, Jeju National University Hospital, 13-15, Aran, Jeju 63241, Republic of Korea

13. Department of Cardiology, Chungnam National University Hospital, 99, Daehak-ro, Yuseong-gu, Daejeon 34134, Republic of Korea

14. Regional Cardiovascular Disease Center, Chungbuk National University Hospital, 776, Sunhwan-ro, Seowon-gu, Cheongju 28644, Republic of Korea

15. Division of Cardiology, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, 44, Suncheonhyang 4-gil, Dongnam-gu, Cheonan-si 31151, Republic of Korea

Abstract

Background/Objectives: Self-recognition of recurrent myocardial infarction (re-MI) may be essential for reducing prehospital time contrast to awareness of re-MI symptoms. However, data on the current status and clinical impact of self-recognition of re-MI are limited in the contemporary period. Thus, this study aimed to increase this body of knowledge. Methods: We enrolled 1018 patients with re-MI using data from the Korean Registry of Acute Myocardial Infarction for Regional Cardiocerebrovascular Centres. The patients were classified into self-recognised MI and unrecognised MI groups, and the differences between them were compared. Results: The rate of self-recognition among the patients with previous experience of MI was only 52.4%. Among the patients with re-MI, factors associated with self-recognition included recent first MI within 3 years, prior dyslipidaemia, two or more MI symptoms, and the male gender (p < 0.05). Factors associated with a lack of recognition were older age (≥70 years), prior stroke, and cancer history (p < 0.05). The proportion of symptoms-to-emergency room arrival time within 90 min among the patients with ST-elevation MI was significantly higher in the self-recognised group than in the unrecognised group (52.6% vs. 31.6%, p < 0.001). The self-recognised group showed a lower in-hospital mortality rate (1.5% vs. 6.2%, p < 0.001), and this benefit was maintained even after 1 year (hazard ratio: 0.53; p < 0.001). Conclusions: Only half of the patients who previously experienced a MI recognised a re-MI when it occurred. This recognition reduced prehospital delay and led to higher survival rates, which highlights the importance of patient education as well as objective monitoring devices, irrespective of individual recognition ability for immediate response.

Funder

Ministry of Health and Welfare of Korea

Publisher

MDPI AG

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