Hepatitis Delta Virus–Host Protein Interactions: From Entry to Egress-Reference-Cited by-同舟云学术

Hepatitis Delta Virus–Host Protein Interactions: From Entry to Egress

Published:2023-07-11 Issue:7 Volume:15 Page:1530
ISSN:1999-4915
Container-title:Viruses
language:en
Short-container-title:Viruses

Author:

Stephenson-Tsoris Susannah¹,Liang T. Jake¹^ORCID

Affiliation:

1. Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, MD 20892, USA

Abstract

Hepatitis delta virus (HDV) is the smallest known human virus and causes the most severe form of human viral hepatitis, yet it is still not fully understood how the virus replicates and how it interacts with many host proteins during replication. This review aims to provide a systematic review of all the host factors currently known to interact with HDV and their mechanistic involvement in all steps of the HDV replication cycle. Finally, we discuss implications for therapeutic development based on our current knowledge of HDV–host protein interactions.

Funder

Intramural Research Program of the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, USA

Publisher

MDPI AG

Subject

Virology,Infectious Diseases

Link

https://www.mdpi.com/1999-4915/15/7/1530/pdf

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