Preparation and Characterization of Zinc Ferrite and Gadolinium Iron Garnet Composite for Biomagnetic Applications

Author:

Costa Bárbara1ORCID,Carvalho João1ORCID,Gavinho Sílvia1ORCID,Vieira Tânia2,Silva Jorge Carvalho2ORCID,Soares Paula I. P.3ORCID,Valente Manuel A.1ORCID,Soreto Sílvia1ORCID,Graça Manuel1ORCID

Affiliation:

1. i3N and Department of Physics, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal

2. i3N/CENIMAT, Physics Department, NOVA School of Science and Technology, Campus de Caparica, NOVA University Lisbon, 2829-516 Caparica, Portugal

3. i3N/CENIMAT, Science Materials Department, Faculty of Sciences and Technology, Nova University of Lisbon, 2829-516 Caparica, Portugal

Abstract

Cancer is a major worldwide public health problem. Although there have already been astonishing advances in cancer diagnosis and treatment, the scientific community continues to make huge efforts to develop new methods to treat cancer. The main objective of this work is to prepare, using a green sol–gel method with coconut water powder (CWP), a new nanocomposite with a mixture of Gd3Fe5O12 and ZnFe2O4, which has never been synthesized previously. Therefore, we carried out a structural (DTA-TG and X-ray diffraction), morphological (SEM), and magnetic (VSM and hyperthermia) characterization of the prepared samples. The prepared nanocomposite denoted a saturation magnetization of 11.56 emu/g at room temperature with a ferromagnetic behavior and with a specific absorption rate (SAR) value of 0.5 ± 0.2 (W/g). Regarding cytotoxicity, for concentrations < 10 mg/mL, it does not appear to be toxic. Although the obtained results were interesting, the high particle size was identified as a problem for the use of this nanocomposite.

Funder

national funds

Publisher

MDPI AG

Reference40 articles.

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4. Bayda, S., Adeel, M., Tuccinardi, T., Cordani, M., and Rizzolio, F. (2020). The History of Nanoscience and Nanotechnology: From Chemical–Physical Applications to Nanomedicine. Molecules, 25.

5. Radioactive Organic Semiconducting Polymer Nanoparticles for Multimodal Cancer Theranostics;Yu;J. Colloid Interface Sci.,2022

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