Enhancing Metabolism and Milk Production Performance in Periparturient Dairy Cattle through Rumen-Protected Methionine and Choline Supplementation

Author:

Huang Bingjian12,Khan Muhammad Zahoor13,Kou Xiyan1,Chen Yinghui1,Liang Huili1,Ullah Qudrat3ORCID,Khan Nadar4,Khan Adnan5ORCID,Chai Wenqiong1ORCID,Wang Changfa1

Affiliation:

1. Liaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding, Liaocheng University, Liaocheng 252000, China

2. College of Life Sciences, Liaocheng University, Liaocheng 252059, China

3. Faculty of Veterinary and Animal Sciences, University of Agriculture, Dera Ismail Khan 29220, Pakistan

4. Livestock and Dairy Development (Research) Department Khyber Pakhtunkhwa, Peshawar 25120, Pakistan

5. Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 511464, China

Abstract

For dairy cattle to perform well throughout and following lactations, precise dietary control during the periparturient phase is crucial. The primary issues experienced by periparturient dairy cows include issues like decreased dry matter intake (DMI), a negative energy balance, higher levels of non-esterified fatty acids (NEFA), and the ensuing inferior milk output. Dairy cattle have always been fed a diet high in crude protein (CP) to produce the most milk possible. Despite the vital function that dairy cows play in the conversion of dietary CP into milk, a sizeable percentage of nitrogen is inevitably expelled, which raises serious environmental concerns. To reduce nitrogen emissions and their production, lactating dairy cows must receive less CP supplementation. Supplementing dairy cattle with rumen-protected methionine (RPM) and choline (RPC) has proven to be a successful method for improving their ability to use nitrogen, regulate their metabolism, and produce milk. The detrimental effects of low dietary protein consumption on the milk yield, protein yield, and dry matter intake may be mitigated by these nutritional treatments. In metabolic activities like the synthesis of sulfur-containing amino acids and methylation reactions, RPM and RPC are crucial players. Methionine, a limiting amino acid, affects the production of milk protein and the success of lactation in general. According to the existing data in the literature, methionine supplementation has a favorable impact on the pathways that produce milk. Similarly, choline is essential for DNA methylation, cell membrane stability, and lipid metabolism. Furthermore, RPC supplementation during the transition phase improves dry matter intake, postpartum milk yield, and fat-corrected milk (FCM) production. This review provides comprehensive insights into the roles of RPM and RPC in optimizing nitrogen utilization, metabolism, and enhancing milk production performance in periparturient dairy cattle, offering valuable strategies for sustainable dairy farming practices.

Funder

Shandong Province Modern Agricultural Technology System Donkey Industrial Innovation Team

Livestock and Poultry Breeding Industry Project of the Ministry of Agriculture and Rural Affairs

Shandong Rural Revitalization Science and Technology Innovation Action Plan

Open Project of Liaocheng University Animal Husbandry Discipline

Open Project of Shandong Collaborative Innovation Center for Donkey Industry Technology

Research on Donkey Pregnancy Improvement

Liaocheng University Scientific Research Fund

Publisher

MDPI AG

Subject

Molecular Biology,Biochemistry,Endocrinology, Diabetes and Metabolism

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