Notes from the 2022 Folate, Vitamin B12, and One-Carbon Metabolism Conference

Author:

Maynard Adam G.123,Petrova Boryana13ORCID,Kanarek Naama134ORCID

Affiliation:

1. Department of Pathology, Boston Children’s Hospital, Boston, MA 02115, USA

2. Graduate Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA

3. Harvard Medical School, Boston, MA 02115, USA

4. Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA

Abstract

Here, we present notes from the Folate, Vitamin B12, and One-Carbon Metabolism Conference organized by The Federation of American Societies for Experimental Biology (FASEB), held in Asheville, North Carolina, USA, 14–19 August 2022. We aim to share the most recent findings in the field with members of our scientific community who did not attend the meeting and who are interested in the research that was presented. The research described includes discussions of one-carbon metabolism at the biochemical and physiological levels and studies of the role of folate and B12 in development and in the adult, and from bacteria to mammals. Furthermore, the summarized studies address the role of one-carbon metabolism in disease, including COVID-19, neurodegeneration, and cancer.

Funder

Charles H. Hood Foundation

Gabrielle’s Angels Foundation for Cancer Research

The Smith Family Awards Program for Excellence in Biomedical Research

Research and Recruitment Funding by BCH

Landry Cancer Biology Consortium

Publisher

MDPI AG

Subject

Molecular Biology,Biochemistry,Endocrinology, Diabetes and Metabolism

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