The Metabolism and Immune Environment in Diffuse Large B-Cell Lymphoma-Reference-Cited by-同舟云学术

The Metabolism and Immune Environment in Diffuse Large B-Cell Lymphoma

Published:2023-06-08 Issue:6 Volume:13 Page:734
ISSN:2218-1989
Container-title:Metabolites
language:en
Short-container-title:Metabolites

Author:

Wu Jianbo¹²^ORCID,Meng Fuqing³,Ran Danyang³,Song Yalong⁴,Dang Yunkun⁴,Lai Fan⁴,Yang Longyan⁵,Deng Mi¹²³^ORCID,Song Yuqin¹,Zhu Jun¹

Affiliation:

1. Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Lymphoma, Peking University Cancer Hospital & Institute, Beijing 100142, China

2. Peking University International Cancer Institute, Health Science Center, Peking University, Beijing 100191, China

3. School of Basic Medical Sciences, Health Science Center, Peking University, Beijing 100191, China

4. Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650500, China

5. Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China

Abstract

Cells utilize different metabolic processes to maintain their growth and differentiation. Tumor cells have made some metabolic changes to protect themselves from malnutrition. These metabolic alterations affect the tumor microenvironment and macroenvironment. Developing drugs targeting these metabolic alterations could be a good direction. In this review, we briefly introduce metabolic changes/regulations of the tumor macroenvironment and microenvironment and summarize potential drugs targeting the metabolism in diffuse large B-cell lymphoma.

Funder

National Natural Science Foundation of China

Beijing Natural Science Foundation

Capital’s Funds for Health Improvement and Research

Beijing Municipal Science & Technology Commission

Chinese Society of Clinical Oncology-Nuocheng Jianhua Blood Tumor Research

Publisher

MDPI AG

Subject

Molecular Biology,Biochemistry,Endocrinology, Diabetes and Metabolism

Link

https://www.mdpi.com/2218-1989/13/6/734/pdf

Reference141 articles.

1. Immunometabolic rewiring in tumorigenesis and anti-tumor immunotherapy;Lian;Mol. Cancer,2022

2. An Update to Hallmarks of Cancer;Ravi;Cureus,2022

3. Diffuse Large B-Cell Lymphoma;Sehn;N. Engl. J. Med.,2021

4. Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response;Monti;Blood,2005

5. The potential role of glycogen metabolism in diffuse large B-cell lymphoma;Jalali;Leuk. Lymphoma,2020