Characterisation of a Silicon Photomultiplier Based Oncological Brachytherapy Fibre Dosimeter

Author:

Caccia Massimo1,Giaz Agnese1,Galoppo Marco1,Santoro Romualdo1ORCID,Martyn Micheal2ORCID,Bianchi Carla3,Novario Raffaele3,Woulfe Peter3,O’Keeffe Sinead4

Affiliation:

1. Dipartimento di Scienza e Alta Tecnologia, Università degli Studi dell’Insubria, via Valleggio 11, 22100 Como, Italy

2. Radiotherapy Department, Galway Clinic, Doughiska Road, H91 HHT0 Galway, Ireland

3. Ospedale di Circolo di Varese, Università degli Studi dell’Insubria, Viale Borri, 57, 21100 Varese, Italy

4. Optical Fibre Sensors Research Centre, University of Limerick, V94 T9PX Limerick, Ireland

Abstract

Source localisation and real-time dose verification are at the forefront of medical research in brachytherapy, an oncological radiotherapy procedure based on radioactive sources implanted in the patient body. The ORIGIN project aims to respond to this medical community’s need by targeting the development of a multi-point dose mapping system based on fibre sensors integrating a small volume of scintillating material into the tip and interfaced with silicon photomultipliers operated in counting mode. In this paper, a novel method for the selection of the optimal silicon photomultipliers to be used is presented, as well as a laboratory characterisation based on dosimetric figures of merit. More specifically, a technique exploiting the optical cross-talk to maintain the detector linearity in high-rate conditions is demonstrated. Lastly, it is shown that the ORIGIN system complies with the TG43-U1 protocol in high and low dose rate pre-clinical trials with actual brachytherapy sources, an essential requirement for assessing the proposed system as a dosimeter and comparing the performance of the system prototype against the ORIGIN project specifications.

Funder

European Union’s Horizon 2020 Research and Innovation Programme

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Biochemistry,Instrumentation,Atomic and Molecular Physics, and Optics,Analytical Chemistry

Reference27 articles.

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3. Better Radiation Therapy for Cervix Cancer Would Save Lives;Thomas;Int. J. Radiat.-Oncol.-Biol.-Phys.,2014

4. Brachytherapy: State-of-the-art radiotherapy in prostate cancer;Chao;BJU Int.,2015

5. ICRU (1985). Dose and Volume Specification for Reporting Intracavitary Therapy in Gynecology, International Commission on Radiation Units and Measurements Inc. (ICRU). Tech. Rep. 38.

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