Research Progress on Porcine Reproductive and Respiratory Syndrome Virus NSP7 Protein
Author:
Li Huawei1, Luo Qin2, Jing Huiyuan3ORCID, Song Yuzhen3, Kong Weili4ORCID, Zhao Mengmeng2ORCID, Zhu Qingge2
Affiliation:
1. College of Food and Bioengineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450047, China 2. Department of Veterinary Medicine, School of Life Science and Engineering, Foshan University, Foshan 528000, China 3. College of Veterinary Medicine, Henan University of Animal Husbandry and Economy, Zhengzhou 450047, China 4. Gladstone Institutes of Virology and Immunology, University of California, San Francisco, CA 94158, USA
Abstract
Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious and severe infectious disease caused by the PRRS virus (PRRSV). PRRS is characterized by reproductive disorders in sows and respiratory dysfunction in pigs. Non-structural protein 7 (NSP7) is one of the most conserved functional proteins in PRRSV, and it plays an important role in viral replication and humoral immune responses in infected hosts. This review discusses the biological characteristics of NSP7 to provide theoretical support for its application in PRRS diagnosis, novel vaccine design, and therapeutic drug development.
Funder
Henan Science and Technology R&D Program Joint Fund Project Henan Science and Technology Key Project Henan University of Animal Husbandry and Economy
Subject
General Veterinary,Animal Science and Zoology
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