Novel Microwave Synthesis of Copper Oxide Nanoparticles and Appraisal of the Antibacterial Application

Abstract

The exceptional characteristics of bio-synthesized copper oxide nanoparticles (CuO NPs), including high surface-to-volume ratio and high-profit strength, are of tremendous interest. CuO NPs have cytotoxic, catalytic, antibacterial, and antioxidant properties. Fruit peel extract has been recommended as a valuable alternative method due to the advantages of economic prospects, environment-friendliness, improved biocompatibility, and high biological activities, such as antioxidant and antimicrobial activities, as many physical and chemical methods have been applied to synthesize metal oxide NPs. In the presence of apple peel extract and microwave (MW) irradiation, CuO NPs are produced from the precursor CuCl2. 2H2O. With the help of TEM analysis, and BET surface area, the average sizes of the obtained NPs are found to be 25–40 nm. For use in antimicrobial applications, CuO NPs are appropriate. Disk diffusion tests were used to study the bactericidal impact in relation to the diameter of the inhibition zone, and an intriguing antibacterial activity was confirmed on both the Gram-positive bacterial pathogen Staphylococcus aureus and Gram-negative bacterial pathogen Escherichia coli. Moreover, CuO NPs did not have any toxic effect on seed germination. Thus, this study provides an environmentally friendly material and provides a variety of advantages for biomedical applications and environmental applications.