Biocompatibility and Corrosion of Microplasma-Sprayed Titanium and Tantalum Coatings versus Titanium Alloy
Author:
Alontseva Darya12ORCID, Safarova (Yantsen) Yuliya1ORCID, Voinarovych Sergii3ORCID, Obrosov Aleksei4ORCID, Yamanoglu Ridvan5, Khoshnaw Fuad6ORCID, Yavuz Hasan Ismail5ORCID, Nessipbekova Assem1, Syzdykova Aizhan1, Azamatov Bagdat12ORCID, Khozhanov Alexandr12, Weiß Sabine4ORCID
Affiliation:
1. Laboratory of Bioengineering and Regenerative Medicine, National Laboratory Astana, Nazarbayev University, Astana 010000, Kazakhstan 2. School of Digital Technologies and Artificial Intelligence, D. Serikbayev East Kazakhstan Technical University, Ust-Kamenogorsk 070010, Kazakhstan 3. E.O. Paton Electric Welding Institute of NAS of Ukraine, 11 Kazymyr Malevich Street, 03150 Kyiv, Ukraine 4. Department of Physical Metallurgy and Materials Technology, Brandenburg Technical University, 03046 Cottbus, Germany 5. Department of Metallurgical and Materials Engineering, College of Engineering, Kocaeli University, Kocaeli 41380, Turkey 6. School of Engineering and Sustainable Development, De Montfort University, Leicester LE1 9BH, UK
Abstract
This study investigates the in vitro biocompatibility, corrosion resistance, and adhesion strength of a gas abrasive-treated Ti6Al4V alloy, alongside microplasma-sprayed titanium and tantalum coatings. Employing a novel approach in selecting microplasma spray parameters, this study successfully engineers coatings with tailored porosity, roughness, and over 20% porosity with pore sizes up to 200 μm, aiming to enhance bone in-growth and implant integration. This study introduces an innovative methodology for quantifying surface roughness using laser electron microscopy and scanning electron microscopy, facilitating detailed morphological analysis of both the substrate and coatings. Extensive evaluations, including tests for in vitro biocompatibility, corrosion resistance, and adhesive strength, revealed that all three materials are biocompatible, with tantalum coatings exhibiting superior cell proliferation and osteogenic differentiation, as well as the highest corrosion resistance. Titanium coatings followed closely, demonstrating favorable osteogenic properties and enhanced roughness, which is crucial for cell behavior and attachment. These coatings also displayed superior tensile adhesive strengths (27.6 ± 0.9 MPa for Ti and 28.0 ± 4.9 MPa for Ta), surpassing the ISO 13179-1 standard and indicating a robust bond with the substrate. Our findings offer significant advancements in biomaterials for medical implants, introducing microplasma spraying as a versatile tool for customizing implant coatings, particularly emphasizing the superior performance of tantalum coatings in terms of biocompatibility, osteogenic potential, and corrosion resistance. This suggests that tantalum coatings are a promising alternative for enhancing the performance of metal implants, especially in applications demanding high biocompatibility and corrosion resistance.
Funder
Ministry of Science and Higher Education of the Republic of Kazakhstan
Subject
Materials Chemistry,Surfaces, Coatings and Films,Surfaces and Interfaces
Reference69 articles.
1. Stich, T., Alagboso, F., Křenek, T., Kovářík, T., Alt, V., and Docheva, D. (2022). Implant-bone-interface: Reviewing the impact of titanium surface modifications on osteogenic processes in vitro and in vivo. Bioeng. Transl. Med., 7. 2. Metallic implants with properties and latest production techniques: A review;Pandey;Adv. Mater. Process. Technol.,2020 3. Vishwakarma, V., Kaliaraj, G.S., and Amirtharaj Mosas, K.K. (2023). Multifunctional Coatings on Implant Materials—A Systematic Review of the Current Scenario. Coatings, 13. 4. Alontseva, D., Azamatov, B., Safarova, Y., Voinarovych, S., and Nazenova, G. (2023). A Brief Review of Current Trends in the Additive Manufacturing of Orthopedic Implants with Thermal Plasma-Sprayed Coatings to Improve the Implant Surface Biocompatibility. Coatings, 13. 5. Implant biomaterials: A comprehensive review;Saini;World J. Clin. Cases,2015
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