Author:
Xu Qing,Wang Ruixin,Zhang Fan,Wang Ruifang,Wu Long,Lin Bo
Abstract
Carrier particle spray freeze-drying is a new technology with high added value for thermosensitive powder spray freeze-drying. The technology includes the following steps: atomization, coating, freezing, and drying. Due to the action of carrier particles, the condensation of frozen droplets in the conventional spray freeze-drying process is overcome. However, there are many influencing factors involved in the process of freezing coating. The mechanism of the complex droplet collision freezing process still needs to be studied. In this paper, from the perspective of spray freezing coating after atomized droplets collide with low-temperature carrier particles, the coating process and freezing process of single droplets impacting the sphere are analyzed microscopically. The freezing coating processes of static and dynamic carrier particles are reviewed. Moreover, the surface evaluation of powder and equipment development for creating powder products is discussed.
Funder
Key-Area Research and Development Program of Guangdong Province
National Natural Science Foundation of China
Subject
Materials Chemistry,Surfaces, Coatings and Films,Surfaces and Interfaces
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