Research Progress in Superhydrophobic Titanium-Based Implants for Antibacterial Applications

Author:

Rao Qin1,Weng Ling1,Zhang Jinshuang1,Liu Donghao1,Zhang Wenjuan1,Chen Siyuan1,Chen Jialong1,Li Xiangyang1,Qiu Hua1,Cao Ying1ORCID,Li Quanli1,Zheng Shunli1ORCID

Affiliation:

1. College & Hospital of Stomatology, Anhui Medical University, Key Lab. of Oral Diseases Research of Anhui Province, Hefei 230032, China

Abstract

Titanium and its alloys have been extensively used as implant materials in clinic settings. However, implant-associated bacterial infection or inflammation remains a primary cause of implantation failure, which threatens human health, and has already become a global issue. Recently, a superhydrophobic surface endowed with a water contact angle higher than 150° has attracted widespread attention in antibacterial applications for their self-cleaning and low-adhesion properties, which has emerged as an important path in preventing biofilm formation. This review first describes the basic theories of wettability. In the second section, we explain biofilm formation, which is a primary pathogenic occurrence in the development of infection in implants. In the last and most important section, we summarize the progress of superhydrophobic titanium-based implants and recent antibacterial applications. This review will attract great interest from both research scientists and clinicians, which will help to rapidly expand superhydrophobic titanium-based implants for antibacterial applications.

Funder

National Natural Science Foundation of China

Key Research and Development Program of Anhui Province

Anhui Province Translational Medical College Research Fund Project

Anhui Medical University Basic and Clinical Collaborative Research Enhancement Program

Research Improvement Program in Stomatologic Hospital & College of Anhui Medical University

Scientific Research of BSKY

2022 Disciplinary Construction Project in the School of Dentistry, Anhui Medical University

2021 Disciplinary Construction Project in the School of Dentistry, Anhui Medical University

Publisher

MDPI AG

Subject

Materials Chemistry,Surfaces, Coatings and Films,Surfaces and Interfaces

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